Digitoxigenin

CAS 143-62-4C23H34O4Biochemicals & Reagents

Digitoxigenin (CAS: 143-62-4), with the molecular formula C23H34O4 and a molar mass of 374.51 g/mol, is a non-ionic cardenolide. It is a fundamental component in the study of cardiac glycosides and their biological activities. Primarily utilised in research settings, it serves as a critical reagent for investigating mechanisms of cytotoxicity and for the synthesis of related therapeutic compounds, particularly in the field of oncology and cardiovascular research.

IUPAC: 3β,14-Dihydroxy-5β,20(22)-cardenolide,3,14,21-Trihydroxy-20(22)-norcholenic acid lactone,5β,20(22)-Cardenolide-3β,14-diol

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Digitoxigenin (C23H34O4) — chemical structure, CAS 143-62-4; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsDetergentsDetergents A to MNon-Ionic Detergents

01 /Applications

Cancer Cytotoxicity Research

Digitoxigenin has been employed in research studies to evaluate its stereochemical impact on cancer cell cytotoxicity. This application aids in understanding the structure-activity relationships of cardenolides in anti-cancer drug discovery.

Glycosidation Synthesis Studies

This compound has been used in investigations exploring the advantages of gold(I)-catalyzed glycosidation reactions. Specifically, it was used to assemble digitoxin, highlighting its role in the synthesis of complex cardiac glycosides.

Biochemical Research Reagent

As a biochemical and reagent, Digitoxigenin serves as a valuable tool for researchers investigating various biological pathways and molecular interactions within cellular systems. Its specific structure lends itself to detailed mechanistic studies.

02 /Properties

Molecular weight	374.51
Empirical formula	C23H34O4
Application	Digitoxigenin has been used in a study to assess its stereochemical effects in cancer cytotoxicity. 1 It has also been used in a study to investigate the advantage of gold(I)-catalyzed glycosidation of glycosyl o-alkyl benzoates to assemble digitoxin. 2
Melting point	253 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash thoroughly after handling
P301IF SWALLOWED

Protective equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3462 6.1 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	25
Safety statements (S)	45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

143-62-4

MDL number

MFCD00003687

PubChem substance

24894291

Beilstein registry

95448

05 /Additional specifications

Description	non-ionic
Gene Information	rat ... Atp1a1(24211)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Digitoxigenin used for?

Digitoxigenin is used in research to study cancer cytotoxicity and in the synthesis of compounds like digitoxin through gold(I)-catalyzed glycosidation. It serves as a biochemical reagent for detailed molecular and cellular investigations.

What are the CAS number and formula for Digitoxigenin?

The CAS number for Digitoxigenin is 143-62-4, and its molecular formula is C23H34O4.

What grade and purity does Tech Serve Solutions supply for Digitoxigenin?

Tech Serve Solutions supplies Digitoxigenin as a research-grade chemical. The specific purity is available on the Certificate of Analysis upon request. We do not represent this product as USP, BP, or EP grade.

How should Digitoxigenin be handled and stored?

Digitoxigenin is classified as acutely toxic (H300). Handle with extreme care, using appropriate personal protective equipment including eyeshields, face shields, gloves, and a P2 respirator. Store in a cool, dry, well-ventilated area away from incompatible substances.

Is Digitoxigenin packed and shipped internationally by TSS?

Yes, Tech Serve Solutions specialises in supplying and exporting fine chemicals globally. Digitoxigenin is shipped according to international regulations for hazardous materials.

How can I request a sample or quote for Digitoxigenin?

To request a sample or a quote for Digitoxigenin, please contact our sales department via the website or provide your details through the online inquiry form. Our team will respond promptly.