Diethyl methylmalonate
Diethyl methylmalonate (CAS: 609-08-5), with the linear formula CH₃CH(COOC₂H₅)₂, is a significant organic building block and ester compound. Possessing a molecular weight of 174.19 g/mol, this chemical serves as a versatile intermediate in various synthetic processes. Its primary utility lies in chemical synthesis, contributing to the development of more complex molecules across different scientific disciplines.
- IUPAC
- Methylmalonic acid diethyl ester
- Synonyms
- Methylmalonic acid diethyl ester
Intermediate in Organic Synthesis
Diethyl methylmalonate functions as a key building block in organic synthesis, enabling the construction of complex carbon skeletons. Its reactive methylene group allows for facile alkylation and acylation reactions, making it valuable for preparing substituted malonates and related compounds.
Pharmaceutical and Agrochemical Research
This ester is employed in research settings for the synthesis of potential pharmaceutical intermediates and agrochemical compounds. Its structure lends itself to the creation of diverse molecular frameworks with potential biological activity.
Biochemical Fermentation Studies
Diethyl methylmalonate has been utilised in studies investigating biochemical processes, such as its effect on erythromycin fermentation in specific microbial strains. This highlights its relevance in understanding and potentially optimising biotechnological applications.
| Molecular weight | 174.19 |
|---|---|
| Linear formula | CH3CH(COOC2H5)2 |
| Assay | 99% |
| Boiling point | 198-199 °C(lit.)78-80 °C/10 mmHg |
| Density | 1.022 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.413(lit.) |
| Application | Diethyl methylmalonate was used to investigate the effect of direct supplementation of the medium with di-ester of methylmalonate on erythromycin fermentation in Saccharopolyspora erythraea mutB strain1. |
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 82 °C / 179.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethyl methylmalonate used for?
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Diethyl methylmalonate (CAS: 609-08-5) is primarily used as an intermediate in organic synthesis and in research for developing pharmaceutical and agrochemical compounds. It has also been applied in studies related to biochemical fermentation processes.
What is the CAS number and chemical formula for Diethyl methylmalonate?
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The CAS number for Diethyl methylmalonate is 609-08-5, and its linear chemical formula is CH₃CH(COOC₂H₅)₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diethyl methylmalonate with an assay of 99%. This product is generally considered a technical or research grade, and TSS does not represent it as USP, BP, or EP grade unless explicitly stated.
How should Diethyl methylmalonate be handled?
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Handling Diethyl methylmalonate requires appropriate safety precautions, including the use of safety eyeshields and chemical-resistant gloves. For specific respiratory protection, consult the safety data sheet; a multi-purpose combination respirator cartridge or an ABEK type filter may be necessary. It has a flash point of 82 °C (179.6 °F).
Is Diethyl methylmalonate shipped internationally by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Diethyl methylmalonate, and can facilitate international shipments.
How can I request a sample or quote for Diethyl methylmalonate?
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To request a sample or a quote for Diethyl methylmalonate, please contact the Tech Serve Solutions sales team through the provided contact channels on our website.
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