Diethyl maleate
Diethyl maleate (CAS: 141-05-9), a diester with the linear formula C2H5OCOCH=CHCOOC2H5 and a molecular weight of 172.18 g/mol, is a valuable organic building block. Its characteristic reactivity, stemming from the activated double bond and ester functionalities, makes it useful in various chemical synthesis applications. Available from Tech Serve Solutions, it serves as a key intermediate in the production of diverse chemical compounds.
- IUPAC
- Maleic acid diethyl ester
- Synonyms
- Maleic acid diethyl ester

Polymerisation Initiator
Diethyl maleate can be employed in specific polymerisation processes. Its structure allows it to participate in radical polymerisation, influencing the properties of the resulting polymers.
Chemical Synthesis Intermediate
This compound serves as a versatile intermediate in organic synthesis. The presence of a double bond and two ester groups allows for a range of chemical transformations, including Diels-Alder reactions and Michael additions.
Pharmaceutical Precursor
Diethyl maleate can act as a precursor in the synthesis of complex pharmaceutical molecules. Its functional groups offer strategic points for elaboration into pharmacologically active compounds.
Research and Development
In R&D settings, diethyl maleate is utilised for exploring novel synthetic pathways and developing new chemical entities. Its well-defined reactivity profile makes it a reliable reagent for laboratory investigations.
| Molecular weight | 172.18 |
|---|---|
| Linear formula | C2H5OCOCH=CHCOOC2H5 |
| Assay | 97% |
| Boiling point | 225 °C(lit.) |
| Density | 1.064 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.441(lit.) |
| Vapour pressure | 1 mmHg (14 °C) |
| Melting point | −10 °C(lit.) |
| Vapour density | 5.93 (vs air) |
| Autoignition temp | 662 °F |

Hazard statements
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 93 °C / 199.4 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethyl maleate used for?
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Diethyl maleate is used as a chemical synthesis intermediate, a precursor in pharmaceutical synthesis, in polymerisation processes, and in research and development for exploring new chemical entities.
What is the CAS number and formula for Diethyl maleate?
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The CAS number for Diethyl maleate is 141-05-9, and its linear formula is C2H5OCOCH=CHCOOC2H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diethyl maleate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should Diethyl maleate be handled safely?
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Diethyl maleate is a Warning substance that can cause skin irritation (H317) and serious eye irritation (H319). Handle with appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection as indicated by safety data sheets.
Is Diethyl maleate a controlled substance?
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The provided data does not indicate that Diethyl maleate is a controlled substance.
How is Diethyl maleate packed, shipped, and exported?
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Diethyl maleate is packed and shipped according to relevant transportation regulations (e.g., NA 1993, PGIII). Tech Serve Solutions is experienced in global export of chemicals.
How can I request a quote or sample of Diethyl maleate?
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To request a quote or sample of Diethyl maleate, please contact our sales department through the website or by phone, providing your specific requirements.
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