Dibenzyl chloromethyl phosphate
Dibenzyl chloromethyl phosphate (CAS: 258516-84-6) is a versatile organophosphorus compound with the molecular formula C15H16ClO4P and a molecular weight of 326.71 g/mol. It serves as a valuable building block in chemical synthesis, particularly for the preparation of water-soluble prodrugs. Its utility extends to derivatization reactions, especially in analytical chemistry, where it offers improved detection capabilities.
Prodrug Synthesis
This compound is employed in the synthesis of water-soluble prodrugs derived from lipophilic alcohols, phenols, and amines. It offers advantages over similar reagents, leading to higher yields in prodrug formation.
Analytical Derivatization
Dibenzyl chloromethyl phosphate acts as an effective derivatization reagent for analytical purposes. Its improved stability and UV activity make it suitable for detection via HPLC-UV, facilitating easier analysis in chromatography.
Chemical Synthesis Intermediate
As an organic building block, it finds use in various chemical synthesis pathways. Its structure makes it suitable for introducing specific functionalities in complex organic molecules.
| Molecular weight | 326.71 |
|---|---|
| Empirical formula | C15H16ClO4P |
| Assay | ≥97.0% (HPLC)≥97.0% |
| Storage temperature | −20°C |
| Contains / stabiliser | 1% tri-Butylamine as stabilizer |
| Application | Synthesis of water-soluble prodrugs of lipophilic alcohols, phenols and amines. This compound is an improved derivative of the well known Di-tert-butyl chloromethyl phosphate. So it can be detected more easily by HPLC-UV, because of higher stability, higher yields and better UV-activity. |
Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shelf Life | (limited shelf life, expiry date on the label) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dibenzyl chloromethyl phosphate used for?
+
Dibenzyl chloromethyl phosphate is primarily used for the synthesis of water-soluble prodrugs of lipophilic alcohols, phenols, and amines. It also functions as a derivatization reagent, particularly in HPLC-UV analysis, due to its enhanced stability and UV activity compared to older reagents.
What are the CAS number and formula for Dibenzyl chloromethyl phosphate?
+
The CAS number for Dibenzyl chloromethyl phosphate is 258516-84-6, and its empirical formula is C15H16ClO4P.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Dibenzyl chloromethyl phosphate with an assay of ≥97.0% (HPLC) and ≥97.0%. This compound is supplied for research and laboratory use, and TSS does not represent it as USP, BP, or EP grade.
How should Dibenzyl chloromethyl phosphate be handled and stored?
+
Dibenzyl chloromethyl phosphate is classified as harmful if swallowed (H302) and requires careful handling. It should be stored at -20°C and has a limited shelf life, with the expiry date indicated on the label. Please consult the Safety Data Sheet (SDS) for comprehensive handling instructions.
Is Dibenzyl chloromethyl phosphate shipped internationally?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can ship Dibenzyl chloromethyl phosphate worldwide.
How can I request a quote or sample for Dibenzyl chloromethyl phosphate?
+
To request a quote or sample of Dibenzyl chloromethyl phosphate, please contact our sales team through the website or by phone. Please specify the quantity required and your shipping destination.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis