Dibenzyl N,N-diisopropylphosphoramidite
Dibenzyl N,N-diisopropylphosphoramidite (CAS: 108549-23-1) is a key chemical intermediate with a molecular weight of 345.42. This organophosphorus compound, represented by the formula [(CH3)2CH]2NP(OCH2C6H5)2, is primarily utilised as a reagent in nucleotide coupling and the synthesis of nucleosides. Its specific chemical structure makes it valuable in organic synthesis and chemical biology research. Tech Serve Solutions supplies this compound with a high degree of purity for demanding applications.
- Synonyms
- [(CH3)2CH]2NP(OCH2C6H5)2
![Dibenzyl N,N-diisopropylphosphoramidite ([(CH3)2CH]2NP(OCH2C6H5)2) — chemical structure, CAS 108549-23-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F108549-23-1.png&w=3840&q=75)
Nucleotide Synthesis
Dibenzyl N,N-diisopropylphosphoramidite serves as an essential coupling agent in the synthesis of oligonucleotides. It facilitates the formation of phosphodiester bonds crucial for building DNA and RNA sequences.
Organic Synthesis
This phosphoramidite is a versatile building block in various organic synthesis pathways. Its reactive nature allows for the introduction of specific phosphorus-containing functionalities into complex molecules.
Chemical Biology Reagent
Used in research settings, it plays a role in the development of novel biologically active compounds and modified nucleic acids for chemical biology applications.
| Molecular weight | 345.42 |
|---|---|
| Linear formula | [(CH3)2CH]2NP(OCH2C6H5)2 |
| Assay | 90% |
| Grade | technical grade |
| Boiling point | 130 °C/0.55 mmHg(lit.) |
| Density | 1.028 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.535(lit.) |
| Storage temperature | 2-8°C |
| Application | Agent for nucleotide coupling/synthesis.1,2 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 69 °C / 156.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dibenzyl N,N-diisopropylphosphoramidite used for?
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Dibenzyl N,N-diisopropylphosphoramidite is primarily used as a reagent for nucleotide coupling and synthesis, and as a building block in organic synthesis and chemical biology.
What is the CAS number and formula for Dibenzyl N,N-diisopropylphosphoramidite?
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The CAS number is 108549-23-1 and the formula is [(CH3)2CH]2NP(OCH2C6H5)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dibenzyl N,N-diisopropylphosphoramidite at a technical grade with an assay of 90%. We do not represent this product as USP, BP, or EP grade.
How should Dibenzyl N,N-diisopropylphosphoramidite be handled safely?
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Dibenzyl N,N-diisopropylphosphoramidite is a Warning substance (H315-H319-H335) causing skin, eye, and respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation. Refer to the Safety Data Sheet for full details.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions offers flexible packing options and securely packages products for global export. Please contact us for specific shipping and export inquiries.
How can I request a sample or quote for Dibenzyl N,N-diisopropylphosphoramidite?
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To request a sample or a quotation, please use the contact form on our website or reach out to our sales department directly.
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