Dibenzyl dicarbonate
Dibenzyl dicarbonate (CAS 31139-36-3) is a chemical reagent with the linear formula (CO2CH2C6H5)2O and a molecular weight of 286.28 g/mol. It is primarily utilised as a reagent for the effective introduction of the benzyloxycarbonyl (Z) protecting group onto amino acids and other amines. This compound is valuable in organic synthesis, particularly in peptide chemistry and the modification of amine functionalities.
- IUPAC
- Dibenzyl pyrocarbonate,Z2O
Amine Protection
Dibenzyl dicarbonate serves as a crucial reagent for the introduction of the benzyloxycarbonyl (Z) protecting group. This protection is widely employed in peptide synthesis and the derivatisation of primary and secondary amines.
Peptide Chemistry
In peptide synthesis, Dibenzyl dicarbonate is instrumental in protecting the alpha-amino group of amino acids. The Z group is stable under various reaction conditions and can be readily removed by hydrogenolysis.
Organic Synthesis Reagent
This compound functions as a versatile reagent in broader organic synthesis for the protection of amines, facilitating complex molecular constructions by temporarily masking reactive amine functionalities.
| Molecular weight | 286.28 |
|---|---|
| Linear formula | (CO2CH2C6H5)2O |
| Assay | 97% |
| Density | 1.17 g/mL at 25 °C(lit.) |
| Application | Reagent for the introduction of the Z-protecting group in amino acids1 and other amines.2 |
| Melting point | 29-32 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dibenzyl dicarbonate used for?
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Dibenzyl dicarbonate is used as a reagent for the introduction of the benzyloxycarbonyl (Z) protecting group in amino acids and other amines.
What is the CAS number and formula for Dibenzyl dicarbonate?
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The CAS number for Dibenzyl dicarbonate is 31139-36-3, and its linear formula is (CO2CH2C6H5)2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dibenzyl dicarbonate with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should Dibenzyl dicarbonate be handled safely?
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Dibenzyl dicarbonate is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure good ventilation.
How is Dibenzyl dicarbonate packed, shipped, and exported?
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Dibenzyl dicarbonate is carefully packed according to industry standards for safe transport. Tech Serve Solutions is experienced in exporting fine chemicals globally.
How can I request a sample or a quote for Dibenzyl dicarbonate?
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To request a sample or obtain a quotation for Dibenzyl dicarbonate, please contact our sales team through the website or by phone.
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