Diacylglycerol Kinase Inhibitor II

CAS 120166-69-0C28H25F2N3OSBiochemicals & Reagents

Diacylglycerol Kinase Inhibitor II (CAS: 120166-69-0) is a pale yellow solid with the molecular formula C28H25F2N3OS and a molecular weight of 489.58 g/mol. It functions as a specific inhibitor of diacylglycerol kinases (DAGKs), crucial enzymes involved in lipid metabolism and cell signalling pathways. This compound is valuable for research into cellular processes, particularly in the fields of cell biology and neuroscience, aiding investigations into signal transduction and lipid second messengers.

IUPAC: 3-[2-[4-(bis(4-Fluorophenyl)methylene)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone,R59949

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Diacylglycerol Kinase Inhibitor II (C28H25F2N3OS) — chemical structure, CAS 120166-69-0; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCell BiologyD to KD-DIFDiacylglycerol kinaseDiacylglycerol kinase (DAGK)Enzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymes

01 /Applications

Cell Signalling Research

Used as a tool compound to investigate the role of diacylglycerol kinases (DAGKs) in intracellular signalling pathways. It helps researchers understand lipid metabolism and its impact on cellular processes.

Neuroscience Studies

Applicable in neuroscience research to explore the involvement of DAGKs in neuronal function and signalling, potentially contributing to understanding neurological disorders.

Biochemical Assays

Serves as a reagent in biochemical assays designed to study enzyme kinetics and inhibition mechanisms related to DAGK activity.

Drug Discovery Screening

Can be employed in high-throughput screening as a reference compound or a tool for identifying novel therapeutic targets related to DAGK pathways.

02 /Properties

Molecular weight	489.58
Empirical formula	C28H25F2N3OS
Form	solid
Colour	pale yellow
Solubility	0.1 M HCl: slightly soluble0.1 M NaOH: slightly solubleDMSO: solubleH2O: insolubleethanol: solubleethyl acetate: soluble
Storage temperature	−20°C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

120166-69-0

MDL number

MFCD00069258

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Diacylglycerol Kinase Inhibitor II used for?

Diacylglycerol Kinase Inhibitor II is primarily used as a research tool to investigate the function and signalling pathways involving diacylglycerol kinases (DAGKs) in cell biology and neuroscience.

What are the CAS number and formula for Diacylglycerol Kinase Inhibitor II?

The CAS number is 120166-69-0 and the empirical formula is C28H25F2N3OS.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product as a research-grade chemical. Specific purity details are available on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Diacylglycerol Kinase Inhibitor II be handled and stored?

Handle with appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, and gloves. Store at -20°C. Avoid dust formation and inhalation, and contact with skin and eyes. It is classified as a Warning with hazards H315, H319, and H335.

Is this product available for international export?

Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, and this product can be shipped internationally. Please contact us for export details.

How can I request a sample or quote for Diacylglycerol Kinase Inhibitor II?

To request a sample or a formal quotation, please contact our sales department via the website or direct email, providing your shipping details and required quantity.