Dibromobimane
Dibromobimane (CAS: 68654-25-1, C10H10Br2N2O2, MW: 350.01) is a bifunctional thiol reagent from Tech Serve Solutions. This compound serves as a valuable cross-linking agent, particularly useful in biochemical research for cysteine mapping and investigations into protein structure, conformation, and cross-linking mechanisms. Its suitability for fluorescence applications makes it a versatile tool in advanced analytical techniques.
Cysteine Mapping
Dibromobimane can be employed to selectively label and map cysteine residues within proteins, aiding in the elucidation of protein structure and function.
Protein Structure Analysis
As a cross-linking agent, it facilitates studies on protein conformation and structural dynamics by forming covalent bonds between specific amino acid residues.
Fluorescence-Based Assays
Its inherent fluorescent properties make Dibromobimane suitable for developing fluorescence-based detection methods for thiols and related biomolecules.
| Molecular weight | 350.01 |
|---|---|
| Empirical formula | C10H10Br2N2O2 |
| Assay | ≥95.0% (CHN) |
| Solubility | DMF: solubleacetonitrile: solublechloroform: soluble |
| Storage temperature | 2-8°C |
| Application | Dibromobimane, a bifunctional thiol reagent, is used as a cross-linking agent for cysteine mapping and studies on protein structure/conformation and cross-linking processes. |
| Suitability | suitable for fluorescence |
| Melting point | 170-172 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioReagent |
|---|---|
| Fluorescence | λex 391 nm in methanolλex 393 nm; λem 477 nm in 0.1 M Tris pH 7.0, gutathione red |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dibromobimane primarily used for?
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Dibromobimane is primarily used as a bifunctional thiol reagent for cysteine mapping and for studies on protein structure, conformation, and cross-linking processes. It is also suitable for fluorescence applications.
What is the CAS number and chemical formula for Dibromobimane?
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The CAS number for Dibromobimane is 68654-25-1, and its chemical formula is C10H10Br2N2O2.
What grade and purity does Tech Serve Solutions supply Dibromobimane at?
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Tech Serve Solutions supplies Dibromobimane with an assay of ≥95.0% (CHN). This product is not supplied as USP, BP, EP, or other pharmacopoeia grades and is intended for research and laboratory use.
How should Dibromobimane be handled and stored safely?
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Dibromobimane is a warning-level substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, and gloves. Store at 2-8°C.
Is Dibromobimane a controlled substance?
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The provided data does not indicate that Dibromobimane is a controlled substance.
How is Dibromobimane packaged and shipped?
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Tech Serve Solutions offers Dibromobimane for export. Specific packaging and shipping details are available upon request.
How can I request a quote or sample for Dibromobimane?
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To request a quote or sample of Dibromobimane, please contact our sales department through the website or by phone.
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