(DHQD)2Pyr
(DHQD)2Pyr (CAS: 149725-81-5) is a chiral ligand with the empirical formula C56H60N6O4 and a molecular weight of 881.11 g/mol. Derived from hydroquinidine, this compound is widely recognised for its efficacy in asymmetric synthesis, particularly in promoting highly enantioselective reactions. It serves as a valuable tool in catalysis, enabling chemists to control stereochemistry with precision in the synthesis of complex molecules.
- IUPAC
- Hydroquinidine-2,5-diphenyl-4,6-pyrimidinediyl diether
Asymmetric Dihydroxylation Ligand
This compound is a key chiral ligand used in asymmetric dihydroxylation reactions, a fundamental transformation for introducing vicinal diols stereoselectively. It enables high enantioselectivity in the formation of chiral diols from olefins.
Catalysis in Organic Synthesis
As a privileged ligand, (DHQD)2Pyr is instrumental in various catalytic asymmetric transformations beyond dihydroxylation. It facilitates stereocontrolled synthesis of complex organic molecules, contributing to pharmaceutical and fine chemical production.
Chiral Auxiliary
In specific synthetic strategies, it can function as a chiral auxiliary. Its well-defined stereochemistry allows for the induction of chirality in target molecules, making it valuable in multi-step syntheses.
| Molecular weight | 881.11 |
|---|---|
| Empirical formula | C56H60N6O4 |
| Assay | 97% |
| Optical activity | [α]20/D −390°, c = 1.2 in methanol |
| Melting point | 247-250 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (DHQD)2Pyr used for?
+
(DHQD)2Pyr is primarily used as a chiral ligand in asymmetric catalysis, notably in asymmetric dihydroxylation reactions, to achieve high enantioselectivity in the synthesis of chiral compounds.
What are the CAS number and formula for (DHQD)2Pyr?
+
The CAS number for (DHQD)2Pyr is 149725-81-5, and its empirical formula is C56H60N6O4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (DHQD)2Pyr with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmaceutical grade.
How should (DHQD)2Pyr be handled safely?
+
This compound is a Warning irritant (H315-H319-H335). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation. Store in a dry, well-ventilated place.
Is (DHQD)2Pyr a controlled substance?
+
The provided data does not indicate that (DHQD)2Pyr is a controlled substance.
How is (DHQD)2Pyr packed and exported?
+
(DHQD)2Pyr is carefully packed according to industry standards to ensure safe transit and is exported globally by Tech Serve Solutions.
How can I request a quote or sample for (DHQD)2Pyr?
+
To request a quote or sample for (DHQD)2Pyr, please contact our sales team through the website or via direct inquiry, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis