Dexamethasone 21-acetate
Dexamethasone 21-acetate (CAS: 1177-87-3), with the molecular formula C24H31FO6 and a molecular weight of 434.50 g/mol, is a synthetic glucocorticoid. This compound is recognised for its potent anti-inflammatory and immunosuppressive properties. It is widely utilised in scientific research for studying cellular pathways, immune responses, and in the development of novel therapeutic agents, serving as a critical tool in biological and pharmacological investigations.
- IUPAC
- 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate,9α-Fluoro-16α-methylprednisolone-21-acetate,Prednisolone F acetate
- Synonyms
- 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate9α-Fluoro-16α-methylprednisolone-21-acetatePrednisolone F acetate
Research into Glucocorticoid Receptor Signalling
Dexamethasone 21-acetate is used as a pharmacological tool to investigate the intricate mechanisms of the glucocorticoid receptor pathway. It helps researchers understand how this receptor regulates gene expression and cellular functions related to inflammation and immunity.
Immunomodulatory Studies
The compound serves as a model in studies focused on immune system modulation. Researchers employ it to explore its effects on immune cell activity and cytokine production, aiding in the understanding of immune homeostasis and disease processes.
Cellular Biology Investigations
In cell biology, Dexamethasone 21-acetate is employed to induce specific cellular responses, allowing for the examination of differentiation, apoptosis, and metabolic changes. Its predictable effects make it valuable for experimental design in various cell-based assays.
Neuroscience Research
This acetate derivative is also used in neuroscience research to study the role of glucocorticoids in the central nervous system. Its applications include investigating neuroinflammation, neuronal survival, and the impact of stress hormones on brain function.
| Molecular weight | 434.50 |
|---|---|
| Empirical formula | C24H31FO6 |
| Assay | ≥99% |
| Storage temperature | 2-8°C |
Hazard statements
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dexamethasone 21-acetate used for?
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Dexamethasone 21-acetate is primarily used in scientific research to study glucocorticoid receptor signalling, immunomodulation, cellular biology, and neuroscience due to its potent anti-inflammatory and immunosuppressive properties.
What is the CAS number and formula for Dexamethasone 21-acetate?
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The CAS number for Dexamethasone 21-acetate is 1177-87-3, and its empirical formula is C24H31FO6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dexamethasone 21-acetate with an assay of ≥99%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should Dexamethasone 21-acetate be handled safely?
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Dexamethasone 21-acetate is classified as a sensitiser (H317). Handle with appropriate personal protective equipment including a dust mask (type N95 US recommended), eyeshields, face shields, and gloves. Ensure adequate ventilation and avoid dust formation. Store at 2-8°C.
Is Dexamethasone 21-acetate a controlled substance?
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Information regarding controlled substance status is not provided in the product data. Please consult relevant local regulations for specific handling and procurement requirements.
How is Dexamethasone 21-acetate packed, shipped, and exported?
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Dexamethasone 21-acetate is carefully packed and prepared for shipment according to international regulations for chemical export. For detailed information on shipping and export services, please contact our sales team.
How can I request a sample or quote for Dexamethasone 21-acetate?
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To request a sample or a quote for Dexamethasone 21-acetate, please contact the Tech Serve Solutions sales department via our website or by phone, providing your specific requirements.
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