Desloratadine

CAS 100643-71-8C19H19ClN2Cell Biology

Desloratadine (CAS: 100643-71-8) is a potent histamine H1 receptor antagonist with the molecular formula C19H19ClN2 and a molecular weight of 310.82 g/mol. This compound serves as a valuable research tool in pharmacology and cell biology, particularly for studies involving histamine signaling pathways and related physiological responses. Its well-defined chemical structure and high purity make it suitable for investigating receptor interactions and cellular mechanisms.

IUPAC: 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H- benzo[5,6]cyclohepta[1,2,b]pyridine,Clarinex®
Synonyms: 100643-71-8

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Desloratadine (C19H19ClN2) — chemical structure, CAS 100643-71-8; Life Science, fine chemical supplied by Tech Serve Solutions

AgonistsBioactive Small MoleculesCell BiologyD-DIFHistaminergicsNeuroscienceNeurotransmissionNeurotransmitters More...

01 /Applications

Pharmacological Research

Desloratadine is employed in vitro and in vivo research settings to study histamine H1 receptor antagonism and its downstream effects on cellular signaling pathways relevant to allergic responses and inflammation. Its role as a selective antagonist makes it useful for dissecting the specific contributions of H1 receptors in complex biological systems.

Neuroscience Research

As a compound influencing neurotransmission, Desloratadine is utilised in neuroscience research to investigate the role of histamine in central nervous system functions and its interaction with other neurotransmitter systems. Studies may focus on its effects on neuronal excitability and receptor dynamics.

Bioactive Small Molecule Studies

Desloratadine falls under the category of bioactive small molecules, making it relevant for screening assays and target identification in drug discovery programs. Researchers can utilise it to validate potential therapeutic targets or explore new pharmacological applications.

02 /Properties

Molecular weight	310.82
Empirical formula	C19H19ClN2
Assay	≥98% (HPLC)
Form	powder
Solubility	DMSO: >10 mg/mL
Storage temperature	2-8°C

03 /Identifiers & registry

CAS number

100643-71-8

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is Desloratadine used for?

Desloratadine is primarily used as a research chemical for pharmacological studies, particularly investigating histamine H1 receptor antagonism, cell signaling, and neuroscience applications.

What are the CAS number and molecular formula for Desloratadine?

The CAS number for Desloratadine is 100643-71-8, and its molecular formula is C19H19ClN2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Desloratadine with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety and handling considerations for Desloratadine?

Desloratadine has a WGK Germany rating of 3, indicating it is hazardous. Handle with appropriate personal protective equipment in a well-ventilated area. Consult the Safety Data Sheet (SDS) for detailed hazard information and handling procedures.

How is Desloratadine packed, shipped, and exported?

Desloratadine is typically supplied as a powder and stored at 2-8°C. TSS is an experienced global supplier and exporter of fine chemicals, handling all necessary documentation and logistics for international shipment.

How can I request a sample or quote for Desloratadine?

To request a sample or quote for Desloratadine, please contact our sales team through the TSS website, providing your specific requirements and contact information.