Dextrorphan
Dextrorphan (CAS: 125-73-5), with the molecular formula C17H23NO and a molecular weight of 257.37 g/mol, is a bioactive small molecule. It is known as the O-demethyl metabolite of dextromethorphan, produced by the CYP2D6 enzyme. This compound plays a role in cell biology and neuroscience research, particularly in studies related to cell signaling and drug metabolism. Dextrorphan is supplied by Tech Serve Solutions for research purposes.
- IUPAC
- (+)-3-Hydroxy-17-methylmorphinan,1,3,4,9,10,10a-Hexahydro-6-hydroxy-2H-10,4a-(iminoethano)-11-methylphenanthrene
Neuroscience Research
Dextrorphan is utilised in neuroscience to investigate NMDA receptor function and neurotransmission pathways. Its role as a metabolite of dextromethorphan aids in understanding the pharmacological effects of opioid-related compounds.
Drug Metabolism Studies
As a significant metabolite of dextromethorphan, Dextrorphan serves as a valuable tool for studying drug and xenobiotic metabolism, particularly the activity of cytochrome P450 enzymes like CYP2D6.
Cell Biology Investigations
This compound is employed in cell biology to explore cellular responses and signalling pathways. Its involvement in drug metabolism research can also extend to studies on multi-drug resistance mechanisms within cells.
| Molecular weight | 257.37 |
|---|---|
| Empirical formula | C17H23NO |
| Colour | white to off-white |
| Solubility | H2O: soluble |
| Optical activity | [α]/D ≥+54° |
| Storage temperature | 2-8°C |
| Application | CYP2D6 O-Demethyl metabolite of dextromethorphan |
| Melting point | ≥195 °C |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... GRIN2A(2903)rat ... Grin2a(24409) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dextrorphan used for?
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Dextrorphan is primarily used in scientific research, particularly in neuroscience and cell biology, to study drug metabolism, NMDA receptor function, and cell signalling pathways. It is the O-demethyl metabolite of dextromethorphan.
What are the CAS number and formula for Dextrorphan?
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The CAS number for Dextrorphan is 125-73-5, and its molecular formula is C17H23NO.
What grade and purity does Tech Serve Solutions supply for Dextrorphan?
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Tech Serve Solutions supplies Dextrorphan for research applications. The specific purity and grade are available upon request; we do not represent this product as USP, BP, or EP grade.
How should Dextrorphan be handled and stored?
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Dextrorphan is classified as harmful if swallowed (H302) and requires careful handling. Recommended personal protective equipment includes a dust mask (type N95), eyeshields, and gloves. Store at 2-8°C.
Is Dextrorphan a controlled substance?
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The provided data does not indicate that Dextrorphan is a controlled substance. However, regulations can vary by jurisdiction, and users should verify local compliance.
How is Dextrorphan packed and exported by TSS?
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Tech Serve Solutions, a specialist global supplier and exporter, ensures appropriate packing for Dextrorphan to maintain its integrity during domestic and international shipment.
How can I request a sample or quote for Dextrorphan?
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To request a sample or a quote for Dextrorphan, please contact the Tech Serve Solutions sales team through our official channels.
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