(−)-Deguelin

CAS 522-17-8C23H22O6Biochemicals & Reagents

(−)-Deguelin (CAS: 522-17-8) is a natural rotenoid with the molecular formula C23H22O6 and a molecular weight of 394.42 g/mol. This compound presents as a white to beige powder. (–)-Deguelin is recognised for its potential as an antitumor agent and its roles in cell biology research, particularly concerning cell signaling pathways. It is often employed as a biochemical tool and reagent in scientific investigations.

IUPAC: (7aS,13aS)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6′,5′-e]pyran-7(7aH)-one

Email us

(−)-Deguelin (C23H22O6) — chemical structure, CAS 522-17-8; Life Science, fine chemical supplied by Tech Serve Solutions

A to CAktAntitumor AgentsBioactive Small MoleculesBiochemicals and ReagentsCancer ResearchCell BiologyD-DIFEnzyme InhibitorsEnzyme Inhibitors by Enzyme

01 /Applications

Cell Biology Research

Used as a research tool to investigate cell signaling pathways, including those involving Akt (Protein Kinase B). Its bioactive properties make it valuable for studying cellular processes and responses.

Antitumor Agent Research

Investigated for its potential as an antitumor agent. Researchers utilise (–)-Deguelin to explore mechanisms of action against cancer cells and to develop novel therapeutic strategies.

Biochemical Studies

Serves as a valuable biochemical reagent for a variety of scientific applications. Its specific inhibitory actions make it useful in enzyme studies and for probing biological mechanisms.

02 /Properties

Molecular weight	394.42
Empirical formula	C23H22O6
Assay	>98% (HPLC)
Form	powder
Colour	white to beige
Solubility	DMSO: soluble10 mg/mL, clear
Storage temperature	−20°C
Melting point	85-87 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

522-17-8

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (–)-Deguelin used for?

(–)-Deguelin is primarily used in scientific research as a tool to investigate cell signaling pathways, particularly those involving Akt (Protein Kinase B), and for its potential as an antitumor agent. It also finds application in biochemical studies.

What is the CAS number and molecular formula for (–)-Deguelin?

The CAS number for (–)-Deguelin is 522-17-8, and its molecular formula is C23H22O6.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (–)-Deguelin with a purity of >98% (HPLC). We do not represent this product as USP, BP, or EP grade.

How should (–)-Deguelin be handled and stored?

(–)-Deguelin should be stored at -20°C. When handling, ensure the use of appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound is classified with WGK Germany 3.

Is (–)-Deguelin a controlled substance?

The provided data does not indicate that (–)-Deguelin is a controlled substance.

How is (–)-Deguelin packed and shipped?

(–)-Deguelin is typically supplied as a white to beige powder. Tech Serve Solutions exports fine chemicals globally, adhering to all necessary shipping regulations.