(−)-Epinephrine

CAS 51-43-4(HO)2C6H3CH(OH)CH2NHCH3Biochemicals & Reagents

(−)-Epinephrine (CAS: 51-43-4) is a crucial catecholamine and a naturally occurring hormone and neurotransmitter. With a molecular weight of 183.20 g/mol, this compound plays a vital role in the body's 'fight-or-flight' response. It is widely used in research for its adrenergic agonist properties, particularly in studies involving cell signalling, cardiovascular function, and neurological pathways.

IUPAC: (−)-Adrenalin,(R)-(−)-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol,L-Adrenaline,L-Epinephrine
Synonyms: (–)-Adrenalin(R)-(–)-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcoholL-AdrenalineL-Epinephrine

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(−)-Epinephrine ((HO)2C6H3CH(OH)CH2NHCH3) — chemical structure, CAS 51-43-4; Life Science, fine chemical supplied by Tech Serve Solutions

AdrenergicsAdrenergics - AgonistsAgonistsBioactive Small MoleculesBiochemicals and ReagentsCatecholamineCell BiologyCofactorGPCR ModulatorsGPCR Proteins

01 /Applications

Pharmacological Research

Investigating the physiological effects of adrenergic stimulation, including its impact on heart rate, blood pressure, and bronchodilation. Used in studies examining receptor binding and signalling pathways.

Biochemical Studies

Serving as a standard for biochemical assays and a tool for understanding metabolic pathways, particularly those related to stress responses and cellular energy regulation.

Neuroscience Research

Utilised in experiments exploring the roles of catecholamines in neurotransmission, mood regulation, and neurological disorders. It is often employed in studies involving dopamine and norepinephrine pathways.

Cell Biology Investigations

Applied in research to understand cellular responses to stress, signal transduction mechanisms, and the function of membrane proteins, including adrenergic receptors.

02 /Properties

Molecular weight	183.20
Linear formula	(HO)2C6H3CH(OH)CH2NHCH3
Solubility	H2O: very slightly solubleNaOH: very solubleacetone: insolublealcohol: very slightly solublechloroform: insolublediethyl ether: insolubleoil: insolublepotassium hydroxide solution: very soluble
Storage temperature	2-8°C
Melting point	215 °C (dec.)(lit.)

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed
H310Fatal in contact with skin

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P280Wear protective gloves, clothing and eye/face protection
P301IF SWALLOWED
P302IF ON SKIN
P310Immediately call a POISON CENTER or doctor

Protective equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 2811 6.1 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	23/24/25
Safety statements (S)	36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

51-43-4

MDL number

MFCD00002204

PubChem substance

24894545

Beilstein registry

2368277

05 /Additional specifications

Gene Information	rat ... Adra1a(29412), Adra2a(25083), Adrb1(24925), Adrb2(24176), Drd1a(24316), Drd2(24318)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is (–)-Epinephrine used for?

(–)-Epinephrine is used in pharmacological and biochemical research to study adrenergic effects, cell signalling, metabolic pathways, and neuroscience, particularly in relation to the 'fight-or-flight' response.

What is the CAS number and formula for (–)-Epinephrine?

The CAS number for (–)-Epinephrine is 51-43-4. Its linear formula is (HO)2C6H3CH(OH)CH2NHCH3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (–)-Epinephrine with a purity assay determined by specification. We do not represent this product as USP, BP, or EP grade unless explicitly stated in the product specifications. Please refer to the Certificate of Analysis for detailed purity information.

How should (–)-Epinephrine be handled and stored?

(–)-Epinephrine is classified as toxic if swallowed, toxic in contact with skin, and toxic if inhaled (H301 + H331, H310). It requires appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges. Store in a cool, dry place at 2-8°C.

Is (–)-Epinephrine a controlled substance?

Based on the provided data, (–)-Epinephrine is not explicitly listed as a controlled substance in the context of RIDADR or other regulatory classifications. However, due to its toxicity (H301+H331, H310), handling should be done with extreme care.

How is (–)-Epinephrine packed and exported?

This product is shipped according to UN 2811, Class 6.1, Packing Group II regulations. Tech Serve Solutions exports globally, adhering to all relevant shipping and customs requirements.

How can I request a sample or quote for (–)-Epinephrine?

To request a sample or quote, please contact our sales team via the website or direct email, providing your specific requirements and shipping details.