DCC
N,N′-Dicyclohexylcarbodiimide (DCC), CAS 538-75-0, with the molecular formula C 12 H 22 N 2 (Molar Mass: 206.33 g/mol), is a widely recognised coupling agent. It is instrumental in organic synthesis, particularly for facilitating the formation of amide and ester bonds. DCC is a cornerstone reagent in peptide synthesis, enabling the efficient condensation of amino acids.
- IUPAC
- N,N′-Dicyclohexylcarbodiimide
- Synonyms
- N,N'-DicyclohexylcarbodiimideDicyclohexylcarbodiimide538-75-0Carbodiimide, N,N'-dicyclohexyl-
Peptide Synthesis
DCC is a primary reagent for activating carboxylic acids, facilitating the formation of peptide bonds between amino acids. Its use is crucial for building peptide chains in both research and industrial settings.
Esterification and Amidation
Beyond peptides, DCC efficiently promotes the formation of ester and amide linkages from their corresponding carboxylic acids and alcohols or amines. This broad utility makes it invaluable in general organic synthesis.
Dehydration Reactions
DCC serves as a potent dehydrating agent. It is employed in various synthetic transformations that involve the removal of water, such as the synthesis of anhydrides and other condensation products.
Chemical Biology Research
As a versatile coupling agent, DCC finds application in chemical biology for modifying biomolecules or synthesising probes. It aids in conjugating different molecular entities for biological studies.
| Molecular weight | 206.33 |
|---|---|
| Linear formula | C6H11N=C=NC6H11 |
| Assay | 99% |
| Boiling point | 122-124 °C/6 mmHg(lit.) |
| Density | 0.898 g/mL at 25 °C |
| Refractive index | n20/D 1.503 |
| Concentration | 60 wt. % in xylenes |
| Melting point | 34-35 °C(lit.) |
Hazard statements
- H317May cause an allergic skin reaction
- H318Causes serious eye damage
- H351Suspected of causing cancer
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P312Call a POISON CENTER if you feel unwell
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 88 °C / 190.4 °F |
| Transport (UN / ADR) | UN 2922 8/PG 2 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | T |
| Risk statements (R) | 22-24-40-41-43 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... EPHX2(2053)mouse ... Ephx2(13850) |
|---|---|
| Matrix | Magnesium aluminometasilicate base material |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is DCC used for?
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DCC (N,N′-Dicyclohexylcarbodiimide) is primarily used as a coupling agent in organic synthesis, particularly for facilitating the formation of amide and ester bonds, and is a key reagent in peptide synthesis.
What are the CAS number and formula for DCC?
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The CAS number for DCC is 538-75-0, and its molecular formula is C 12 H 22 N 2 .
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies DCC with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should DCC be handled safely?
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DCC is a hazardous substance, labelled with Danger signal word. It causes serious eye damage (H318) and may cause an allergic skin reaction (H317) and is suspected of causing cancer (H351). Always use appropriate personal protective equipment including gloves, goggles, and a suitable respirator, and handle in a well-ventilated area.
How is DCC packed, shipped, and exported?
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DCC is carefully packed according to international shipping regulations. As a chemical supplier and exporter since 1998, Tech Serve Solutions has extensive experience in global distribution.
How can I request a sample or quote for DCC?
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To request a sample or a quotation for DCC, please use the contact form on our website or call our sales team directly.
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