DL-1,2-Isopropylideneglycerol
DL-1,2-Isopropylideneglycerol (CAS: 100-79-8) is a versatile organic compound with the molecular formula C6H12O3 and a molecular weight of 132.16 g/mol. This acetal, also known as Solketal, serves as a valuable building block in chemical synthesis. Its miscibility with water and common organic solvents makes it adaptable for various reactions and formulations. It is frequently employed as a starting reagent in the preparation of complex organic molecules and derivatives.
- IUPAC
- (±)-2,2-Dimethyl-1,3-dioxolane-4-methanol,(±)-2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane,1,2-Isopropylidene-rac-glycerol,Solketal
- Synonyms
- Solketal(±)-2,2-Dimethyl-1,3-dioxolane-4-methanol(±)-2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane1,2-Isopropylidene-rac-glycerol

Synthesis of Tulipaline Derivatives
DL-1,2-Isopropylideneglycerol has been utilized as a foundational reagent in the laboratory synthesis of tulipaline derivatives. This application highlights its utility in constructing specific molecular architectures.
Organic Synthesis Building Block
As a protected form of glycerol, this compound is an important intermediate in multi-step organic syntheses. It allows for selective manipulation of other functional groups before deprotection.
Chiral Chemistry Intermediate
DL-1,2-Isopropylideneglycerol can serve as a precursor in the synthesis of chiral molecules, contributing to the development of enantiomerically pure compounds.
| Molecular weight | 132.16 |
|---|---|
| Empirical formula | C6H12O3 |
| Assay | 98% |
| Boiling point | 188-189 °C(lit.) |
| Density | 1.063 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.434(lit.) |
| Solubility | H2O: misciblealcohol: misciblediethyl ether: miscibleoil: misciblepetroleum ether: miscible |
| Application | DL-1,2-Isopropylideneglycerol was used as the starting reagent for synthesis of tulipaline derivatives1. |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 90 °C / 194 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is DL-1,2-Isopropylideneglycerol used for?
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DL-1,2-Isopropylideneglycerol is primarily used as a building block in organic synthesis, notably as a starting reagent for the preparation of tulipaline derivatives and other complex organic molecules.
What is the CAS number and formula for DL-1,2-Isopropylideneglycerol?
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The CAS number is 100-79-8 and the molecular formula is C6H12O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies DL-1,2-Isopropylideneglycerol with an assay of 98%. This product is supplied for research and laboratory use and is not represented as USP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for DL-1,2-Isopropylideneglycerol?
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DL-1,2-Isopropylideneglycerol has a flash point of 90 °C (194 °F). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used when handling this chemical. Refer to the safety data sheet for comprehensive information.
Is DL-1,2-Isopropylideneglycerol a controlled substance?
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Based on the provided data, DL-1,2-Isopropylideneglycerol is not listed as a controlled substance.
How is DL-1,2-Isopropylideneglycerol packed and shipped?
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DL-1,2-Isopropylideneglycerol is packed and shipped according to relevant regulations, including transportation classifications such as NA 1993 / PGIII, ensuring safe transit for domestic and international export.
How can I request a sample or quote for DL-1,2-Isopropylideneglycerol?
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To request a sample or quote for DL-1,2-Isopropylideneglycerol, please contact our sales department through the website or by phone, providing your specific requirements.
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