CyJohnPhos
CyJohnPhos (CAS: 247940-06-3), with the molecular formula C24H31P and a molecular weight of 350.48 g/mol, is a specialised phosphine ligand. It is primarily utilised in palladium-catalysed cross-coupling reactions, facilitating the synthesis of complex organic molecules. This compound is particularly noted for its application in preparing key building blocks for advanced materials and research, contributing to advancements in synthetic organic chemistry.
- IUPAC
- (2-Biphenyl)dicyclohexylphosphine,2-(Dicyclohexylphosphino)biphenyl,Cyclohexyl JohnPhos
- Synonyms
- Cyclohexyl JohnPhos
Palladium-Catalysed Synthesis
CyJohnPhos serves as a crucial ligand in palladium-catalysed reactions, including cross-coupling processes like the Suzuki-Miyaura and Buchwald-Hartwig reactions. Its structure is optimised for enhancing catalytic activity and selectivity in the formation of carbon-carbon and carbon-heteroatom bonds.
Precursor for Ionic Receptors
This ligand is employed in the synthesis of 1,3,5-tris(2′-aminophenyl)benzene, a fundamental component for constructing sophisticated ionic receptors. These receptors have potential applications in molecular recognition and supramolecular chemistry.
Cross-Coupling Reactions
It is a valuable reagent for various cross-coupling methodologies, such as Negishi and Hiyama couplings, enabling efficient and controlled C-X bond formation. Its use aids in the development of novel organic structures.
| Molecular weight | 350.48 |
|---|---|
| Empirical formula | C24H31P |
| Assay | 97% |
| Application | Ligand employed in the palladium-catalysed synthesis of 1,3,5-tris(2′-aminophenyl)benzene, a core building block for potential ionic receptors.1 |
| Melting point | 102-106 °C(lit.) |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Ligand For | ArylationsBuchwald-Hartwig Cross Coupling ReactionC-X Bond FormationHiyama CouplingMethylationsNegishi CouplingOxidationsSuzuki-Miyaura Coupling |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is CyJohnPhos used for?
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CyJohnPhos is used as a phosphine ligand in palladium-catalysed cross-coupling reactions, including arylations, Buchwald-Hartwig coupling, C-X bond formation, Hiyama coupling, methylations, Negishi coupling, oxidations, and Suzuki-Miyaura coupling. It is also applied in synthesising building blocks like 1,3,5-tris(2′-aminophenyl)benzene for potential ionic receptors.
What are the CAS number and formula for CyJohnPhos?
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The CAS number for CyJohnPhos is 247940-06-3, and its empirical formula is C24H31P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies CyJohnPhos with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for CyJohnPhos?
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CyJohnPhos is classified with hazard statement H413, indicating it may cause long-lasting harmful effects to aquatic life. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used. Handle with care in a well-ventilated area.
How is CyJohnPhos typically packed, shipped, and exported?
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CyJohnPhos is carefully packed in compliance with international shipping regulations. As a global supplier, Tech Serve Solutions has extensive experience in exporting fine chemicals worldwide.
How can I request a sample or quote for CyJohnPhos?
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To request a sample or a quote for CyJohnPhos, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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