Cyclohexyldiphenylphosphine
Cyclohexyldiphenylphosphine (CAS: 6372-42-5), with the chemical formula C6H11P(C6H5)2 and a molecular weight of 268.33 g/mol, is a valuable organophosphorus compound. It serves primarily as a ligand in homogeneous catalysis, particularly in cross-coupling reactions. Its structure, featuring a cyclohexyl group and two phenyl groups attached to a phosphorus atom, allows for tunable electronic and steric properties, making it a versatile tool in organic synthesis.
- IUPAC
- Diphenylcyclohexylphosphine
- Synonyms
- Diphenylcyclohexylphosphine

Homogeneous Catalysis
Cyclohexyldiphenylphosphine acts as a key ligand in transition metal catalysis. Its steric and electronic properties are well-suited for promoting various catalytic transformations.
Cross-Coupling Reactions
This phosphine ligand is frequently employed in palladium-catalyzed cross-coupling reactions, such as Suzuki, Heck, and Sonogashira couplings, facilitating the formation of carbon-carbon bonds.
Organic Synthesis
It is a useful reagent in the synthesis of complex organic molecules, where precise control over reaction pathways and selectivity is essential.
Ligand Design
Its structure can be modified or incorporated into more complex ligand frameworks for specialized catalytic applications in academia and industry.
| Molecular weight | 268.33 |
|---|---|
| Linear formula | C6H11P(C6H5)2 |
| Melting point | 58-62 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cyclohexyldiphenylphosphine used for?
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Cyclohexyldiphenylphosphine is primarily used as a ligand in homogeneous catalysis, especially in palladium-catalyzed cross-coupling reactions and other organic synthesis applications.
What are the CAS number and formula for Cyclohexyldiphenylphosphine?
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The CAS number is 6372-42-5, and the chemical formula is C6H11P(C6H5)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cyclohexyldiphenylphosphine primarily as a research or technical grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.
How should Cyclohexyldiphenylphosphine be handled safely?
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Cyclohexyldiphenylphosphine is combustible and has a high flash point. Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store in a well-ventilated area.
How is Cyclohexyldiphenylphosphine packed, shipped, and exported?
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Tech Serve Solutions ensures proper packaging for safe handling, storage, and transportation. We are experienced in exporting fine chemicals globally, adhering to all relevant international shipping regulations.
How can I request a quote or sample for Cyclohexyldiphenylphosphine?
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To request a quote or a sample of Cyclohexyldiphenylphosphine, please contact our sales department through the website or by phone, providing your specific requirements.
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