Cu-TMEDA catalyst
Cu-TMEDA catalyst (CAS: 30698-64-7) is a copper-based coordination complex with the molecular formula C12H34Cl2Cu2N4O2 and a molecular weight of 464.42 g/mol. This compound serves as a valuable catalyst in various organic synthesis reactions, including asymmetric conjugate additions and oxidative coupling copolymerizations. It is supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- Di-μ-hydroxo-bis[(N,N,N′.N′-tetramethylethylenediamine)copper(II)] chloride

Asymmetric Conjugate Addition Reactions
Cu-TMEDA catalyst is employed as a catalyst in asymmetric conjugate addition reactions, facilitating the stereoselective formation of carbon-carbon bonds.
1,3-Dipolar Cycloaddition Reactions
This compound functions as a precatalyst in 1,3-dipolar cycloaddition reactions involving pyrazolidinone-based dipoles and terminal alkynes.
Oxidative N-Arylation of Imidazoles
Cu-TMEDA catalyst is utilized in the oxidative N-arylation of imidazoles, a transformation important for the synthesis of heterocyclic compounds.
Oxidative Coupling Copolymerization
The catalyst facilitates oxidative coupling copolymerization reactions, enabling the synthesis of complex polymeric structures.
Tandem Reactions
It acts as a catalyst in tandem phosphorous-carbon bond formation-oxyfunctionalization reactions, promoting sequential chemical transformations.
Benzylation and Allylation of Amides
Cu-TMEDA catalyst is applied in the benzylation and allylation of amides, contributing to the functionalization of amide groups.
| Molecular weight | 464.42 |
|---|---|
| Empirical formula | C12H34Cl2Cu2N4O2 |
| Application | Catalyst for: • Asymmetric conjugate addition reactions1• 1,3-dipolar cycloaddition of pyrazolidinone-based dipoles to terminal alkynes (precatalyst)2• Oxidative N-arylation of imidazoles3• Oxidative coupling copolymerization4• Tandem phosphorous-carbon bond formation-oxyfunctionalization reactions5• Benzylation and allylation of amides6 |
| Melting point | 131-132 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cu-TMEDA catalyst used for?
+
Cu-TMEDA catalyst is used as a catalyst in various organic synthesis reactions, including asymmetric conjugate addition, 1,3-dipolar cycloaddition, oxidative N-arylation, oxidative coupling copolymerization, tandem phosphorous-carbon bond formation-oxyfunctionalization, and benzylation/allylation of amides.
What is the CAS number and formula for Cu-TMEDA catalyst?
+
The CAS number for Cu-TMEDA catalyst is 30698-64-7, and its empirical formula (Hill notation) is C12H34Cl2Cu2N4O2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Cu-TMEDA catalyst for research and development purposes. The specific assay or grade is available upon request. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What safety precautions should be taken when handling Cu-TMEDA catalyst?
+
When handling Cu-TMEDA catalyst, it is essential to use safety equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Consult the Safety Data Sheet (SDS) for comprehensive handling information.
How is Cu-TMEDA catalyst packed, shipped, and exported?
+
Cu-TMEDA catalyst is carefully packed to ensure integrity during transit. We are experienced in exporting chemicals globally to meet the needs of researchers and industries worldwide.
How can I request a sample or quote for Cu-TMEDA catalyst?
+
To request a sample or a quote for Cu-TMEDA catalyst, please contact our sales team through the website or by phone, providing your specific requirements.
▶ Related products

Benzeneruthenium(II) chloride dimer
Ru2(C6H6)2Cl4
Catalysis & Inorganic
Benzoylferrocene
C17H14FeO
Catalysis & Inorganic
Benzyldiphenylphosphine
C6H5CH2P(C6H5)2
Catalysis & Inorganic
Beryllium
Be
Catalysis & Inorganic
Beryllium oxide
BeO
Catalysis & Inorganic![Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer — chemical structure, CAS 12257-42-0; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F12257-42-0.png&w=3840&q=75)
Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer
Catalysis & Inorganic
![Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo — chemical structure, CAS 1228149-03-8; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1228149-03-8.png&w=3840&q=75)
Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo
1-d:1′
Catalysis & Inorganic![Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride (C16H20ClN3Ni) — chemical structure, CAS 1033772-47-2; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1033772-47-2.png&w=3840&q=75)
Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride
C16H20ClN3Ni
Catalysis & Inorganic▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis