Copper(II) trifluoromethanesulfonate
Copper(II) trifluoromethanesulfonate (CAS 34946-82-2), with the formula (CF3SO3)2Cu and a molecular weight of 361.68 g/mol, is a stable, crystalline copper salt. It is widely recognised as an effective Lewis acid catalyst, finding significant utility in various organic synthesis reactions. Its primary applications lie in promoting condensation, amination, and cyclisation reactions within academic research and industrial chemical development.
- IUPAC
- Copper(II) triflate,Cu(OTf)2,Cupric trifluoromethanesulfonate,Trifluoromethanesulfonic acid copper(II) salt
- Synonyms
- Copper(II) triflateCu(OTf)2Cupric trifluoromethanesulfonateTrifluoromethanesulfonic acid copper(II) salt
Catalyst for Mannich Condensation
Copper(II) trifluoromethanesulfonate serves as an efficient catalyst for promoting the Mannich condensation reaction, a crucial carbon-carbon bond-forming process in organic synthesis.
Promoter for Annulative Amination
This compound facilitates annulative amination reactions, enabling the formation of complex heterocyclic structures through the incorporation of amine functionalities.
Friedel-Crafts Reaction Catalyst
It acts as a Lewis acid catalyst in Friedel-Crafts reactions, facilitating the alkylation and acylation of aromatic rings for the synthesis of substituted aromatic compounds.
Henry Reaction Accelerator
Copper(II) trifluoromethanesulfonate is employed as a catalyst to accelerate the Henry reaction, also known as the nitroaldol reaction, which is vital for creating carbon-carbon bonds.
Carbazole Synthesis
This triflate is instrumental in the hypervalent iodine reagent-mediated preparation and intramolecular oxidative C-N bond formation for synthesising carbazoles, important nitrogen-containing heterocycles.
| Molecular weight | 361.68 |
|---|---|
| Linear formula | (CF3SO3)2Cu |
| Assay | 98% |
| Application | Catalyst for:• Mannich condensation1• Annulative amination2• Friedel-Crafts reaction3• Henry reaction4• Hypervalent iodine reagent-mediated preparation of carbazoles5• Intramolecular oxidative C-N bond formation for the synthesis of carbazoles6 |
| Melting point | ≥300 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Copper(II) trifluoromethanesulfonate used for?
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Copper(II) trifluoromethanesulfonate is primarily used as a catalyst in various organic synthesis reactions, including Mannich condensation, annulative amination, Friedel-Crafts reactions, Henry reactions, and carbazole synthesis.
What are the CAS number and formula for Copper(II) trifluoromethanesulfonate?
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The CAS number is 34946-82-2, and the linear formula is (CF3SO3)2Cu.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Copper(II) trifluoromethanesulfonate with an assay of 98%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Copper(II) trifluoromethanesulfonate be handled safely?
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Copper(II) trifluoromethanesulfonate is classified as corrosive. Handling requires stringent safety measures, including the use of safety glasses, face shields, and appropriate gloves. In areas with potential for dust or aerosol generation, a full-face particle respirator (type N100 US, P1 or P3 EN143) is recommended. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions.
Is Copper(II) trifluoromethanesulfonate a controlled substance?
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The provided data does not indicate that Copper(II) trifluoromethanesulfonate is a controlled substance.
How is Copper(II) trifluoromethanesulfonate packed and shipped?
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Copper(II) trifluoromethanesulfonate is shipped according to international regulations for hazardous materials, designated as UN 3261, Class 8, Packing Group II. Specific packaging will adhere to these regulations.
How can I request a sample or quote for Copper(II) trifluoromethanesulfonate?
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To request a sample or a quote, please contact the TSS sales department via our website or by phone, providing the product name and CAS number (34946-82-2).
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