Cyclopropylmagnesium bromide solution
Cyclopropylmagnesium bromide solution (CAS: 23719-80-4; C3H5BrMg; MW: 145.28) is a Grignard reagent supplied by Tech Serve Solutions. This organometallic compound is a 0.5 M solution in Tetrahydrofuran (THF), known for its reactivity in organic synthesis. It is commonly employed as a versatile building block for introducing the cyclopropyl group into various organic molecules, facilitating the formation of complex structures in pharmaceutical and fine chemical research.
Cyclopropylation Reactions
Serves as a key reagent for introducing the cyclopropyl moiety into organic substrates. This is valuable in the synthesis of pharmaceuticals and agrochemicals where the cyclopropyl group can enhance biological activity or modify physical properties.
Organometallic Synthesis
As a Grignard reagent, it participates in nucleophilic addition reactions with carbonyl compounds (aldehydes, ketones, esters) and other electrophiles. This enables the construction of carbon-carbon bonds and the formation of more complex molecular architectures.
Intermediate for Fine Chemicals
Utilised in multi-step syntheses to produce advanced intermediates for the fine chemical industry. Its specific reactivity allows for targeted functionalization in complex synthetic pathways.
| Molecular weight | 145.28 |
|---|---|
| Empirical formula | C3H5BrMg |
| Boiling point | 65 °C |
| Density | 0.968 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H261In contact with water releases flammable gas
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P422
| Flash point | -30 °C / -22 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Greener Alternative Product Characteristics | Catalysis |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cyclopropylmagnesium bromide solution used for?
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Cyclopropylmagnesium bromide solution is primarily used for cyclopropylation reactions, introducing the cyclopropyl group into organic molecules, and as a versatile Grignard reagent in organometallic synthesis for carbon-carbon bond formation.
What is the CAS number and chemical formula for Cyclopropylmagnesium bromide solution?
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The CAS number is 23719-80-4, and the empirical formula (Hill notation) is C3H5BrMg.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cyclopropylmagnesium bromide solution at a concentration of 0.5 M in THF. We do not represent this product as USP, BP, or EP grade; it is suitable for research and technical applications.
How should Cyclopropylmagnesium bromide solution be handled and stored?
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This compound is highly flammable (H225), reacts violently with water (H261), and causes severe skin burns and eye damage (H314). It may form explosive peroxides. Store under an inert atmosphere at 2-8°C, away from ignition sources. Handle with appropriate personal protective equipment in a well-ventilated area.
Is Cyclopropylmagnesium bromide solution a controlled substance?
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The provided data does not indicate that Cyclopropylmagnesium bromide solution is a controlled substance.
How is Cyclopropylmagnesium bromide solution packed and shipped?
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Cyclopropylmagnesium bromide solution is typically packed in containers suitable for flammable and reactive liquids. As a global supplier and exporter, Tech Serve Solutions adheres to all relevant shipping regulations for hazardous materials.
How can I request a sample or quote for Cyclopropylmagnesium bromide solution?
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To request a sample or quote, please contact our sales team through the website or by phone, providing the product name, CAS number (23719-80-4), and desired quantity.
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