Cyclopropylzinc bromide solution
Cyclopropylzinc bromide solution (CAS: 126403-68-7, C3H5BrZn) is an organozinc reagent supplied by Tech Serve Solutions. With a molecular weight of 186.37 g/mol, this solution is primarily recognised for its utility as an active nucleophile in palladium-catalyzed cross-coupling reactions. It is commonly employed in organic synthesis for introducing the cyclopropyl group into various molecular structures, particularly in the development of complex organic molecules and pharmaceutical intermediates.
Palladium-Catalyzed Cross-Coupling
Serves as an active nucleophile in Pd-catalyzed cross-coupling reactions, particularly with heteroaryl halides. This facilitates the introduction of the cyclopropyl moiety into target molecules, a common strategy in medicinal chemistry and materials science.
Organozinc Reagent in Synthesis
As an organozinc halide, it participates in various organometallic transformations. Its reactivity profile allows for selective C-C bond formation, making it valuable in multi-step synthetic routes.
Synthesis of Complex Molecules
Used in the construction of complex organic frameworks where the incorporation of a cyclopropyl group is desired. This is relevant in the synthesis of agrochemicals, pharmaceuticals, and fine chemicals.
| Molecular weight | 186.37 |
|---|---|
| Empirical formula | C3H5BrZn |
| Density | 0.969 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
| Application | Active nucleophile in Pd-catalyzed cross-coupling of heteroaryl halides.1 |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H336May cause drowsiness or dizziness
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 3399 4.3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-14-19-36/37/38 |
| Safety statements (S) | 16-26 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cyclopropylzinc bromide solution used for?
+
Cyclopropylzinc bromide solution (CAS: 126403-68-7) is primarily used as an active nucleophile in palladium-catalyzed cross-coupling reactions, enabling the introduction of the cyclopropyl group into organic molecules. It is a valuable reagent in chemical synthesis, particularly for constructing complex organic compounds and pharmaceutical intermediates.
What is the CAS number and molecular formula for Cyclopropylzinc bromide solution?
+
The CAS number for Cyclopropylzinc bromide solution is 126403-68-7. Its empirical formula is C3H5BrZn.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Cyclopropylzinc bromide solution at a concentration of 0.5 M in THF. While this is a high-quality reagent suitable for research and synthesis, TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should Cyclopropylzinc bromide solution be handled and stored safely?
+
Cyclopropylzinc bromide solution is flammable (H225) and reacts violently with water. It can cause severe skin burns and eye damage (H314), and may cause respiratory irritation and drowsiness (H335, H336). Store in a cool, dry, well-ventilated area at 2-8°C, away from ignition sources and incompatible materials, particularly water. Handle under an inert atmosphere using appropriate personal protective equipment.
How is Cyclopropylzinc bromide solution shipped and exported?
+
Cyclopropylzinc bromide solution is classified under UN 3399 (Organometallic substance, liquid, water-reactive, flammable, Hazard Class 4.3, Packing Group II). Tech Serve Solutions, as an experienced global supplier and exporter, ensures that all shipments comply with relevant international dangerous goods regulations for safe transport and export.
How can I request a quote or sample?
+
To request a quote or a sample of Cyclopropylzinc bromide solution, please visit the Tech Serve Solutions website or contact our sales team directly. Provide the product name and CAS number (126403-68-7) when making your inquiry.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis