Cystamine dihydrochloride
Cystamine dihydrochloride (CAS: 56-17-7) is a sulfur-containing organic compound with the linear formula NH₂CH₂CH₂SSCH₂CH₂NH₂ · 2HCl and a molecular weight of 225.20 g/mol. This versatile reagent is employed in chemical synthesis, particularly as a building block for organic molecules. Its applications span polymer modification for chromatography, crosslinking in hydrogel development, and functionalisation of nanoparticles for drug delivery systems.
- IUPAC
- 2,2′-Diaminodiethyl disulfide dihydrochloride,2,2′-Dithiobis(ethylamine) dihydrochloride,Decarboxycystine dihydrochloride
- Synonyms
- 2,2′-Dithiobis(ethylamine) dihydrochloride2,2′-Diaminodiethyl disulfide dihydrochloride

Polymer Monolith Derivatization
Cystamine dihydrochloride serves as a valuable reagent for derivatising polymer monoliths. This modification enhances their utility in hydrophilic interaction liquid chromatography (HILIC) applications.
Hydrogel Crosslinking Agent
In the field of materials science, it functions as an effective crosslinking agent. This is particularly relevant in the development and synthesis of advanced polymer hydrogels.
Nanoparticle Functionalisation
The compound is utilised to functionalise nanoparticles. These engineered nanoparticles find applications in sophisticated delivery systems for nucleic acids like siRNA and DNA.
| Molecular weight | 225.20 |
|---|---|
| Linear formula | NH2CH2CH2SSCH2CH2NH2 · 2HCl |
| Assay | 96% |
| Application | Cystamine dihydrochloride is a useful reagent to derivatize various polymer monoliths for hydrophilic interaction liquid chromatography; as a crosslinking agent in the development of polymer hydrogels; and as a functional group in nanoparticles developed for siRNA and DNA delivery. |
| Melting point | 217-220 °C (dec.)(lit.) |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cystamine dihydrochloride used for?
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Cystamine dihydrochloride is used as a reagent to derivatise polymer monoliths for hydrophilic interaction liquid chromatography, as a crosslinking agent in polymer hydrogel development, and as a functional group in nanoparticles for siRNA and DNA delivery.
What are the CAS number and formula for Cystamine dihydrochloride?
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The CAS number is 56-17-7 and the linear formula is NH₂CH₂CH₂SSCH₂CH₂NH₂ · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cystamine dihydrochloride with an assay of 96%. This product is suitable for research and general chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should Cystamine dihydrochloride be handled safely?
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Cystamine dihydrochloride is classified with the GHS hazard statement H302 (Harmful if swallowed). Appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves, should be worn when handling this compound. Ensure adequate ventilation.
How is Cystamine dihydrochloride packed and shipped?
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Cystamine dihydrochloride is carefully packaged to maintain its integrity during transport. Tech Serve Solutions exports this chemical globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for Cystamine dihydrochloride?
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To request a sample or a quote for Cystamine dihydrochloride, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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