Cyclophosphamide monohydrate
Cyclophosphamide monohydrate (CAS: 6055-19-2), with the empirical formula C7H15Cl2N2O2P · H2O and a molecular weight of 279.10 g/mol, is a vital antineoplastic agent. It functions as an alkylating agent, primarily used in chemotherapy for various cancers and as an immunosuppressant. This compound plays a significant role in cancer research and cell biology studies, particularly in understanding DNA modification and repair mechanisms.
- IUPAC
- 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide,Cytoxan
- Synonyms
- 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, monohydrate,Cytoxan
Antineoplastic Agent
Cyclophosphamide monohydrate is utilised as a key chemotherapeutic agent in the treatment of various malignancies. Its mechanism involves alkylating DNA, thereby inhibiting cancer cell proliferation.
Immunosuppressant Therapy
Beyond cancer treatment, this compound serves as an immunosuppressant. It is employed in managing certain autoimmune diseases and in preventing graft-versus-host disease following organ transplantation.
Cancer Research
Its well-defined cytotoxic effects make cyclophosphamide monohydrate a valuable tool in cancer research, aiding in the study of tumour biology and the development of novel therapeutic strategies.
Cell Biology Studies
Researchers utilise cyclophosphamide monohydrate in cell biology to investigate cellular responses to DNA damage and to explore mechanisms of cell death and repair.
| Molecular weight | 279.10 |
|---|---|
| Empirical formula | C7H15Cl2N2O2P · H2O |
| Solubility | Do you have solubility information on this product that you would like to share? |
| Storage temperature | 2-8°C |
| Application | Do you have application information on this product that you would like to share? |
| Melting point | 49-51 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P301IF SWALLOWED
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3464 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-25 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cyclophosphamide monohydrate primarily used for?
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Cyclophosphamide monohydrate is primarily used as an antineoplastic agent in chemotherapy and as an immunosuppressant.
What are the CAS number and formula for Cyclophosphamide monohydrate?
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The CAS number is 6055-19-2, and the empirical formula is C7H15Cl2N2O2P · H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies cyclophosphamide monohydrate as a research-grade chemical. We do not represent it as USP, BP, or EP grade. Please refer to the product specifications for available purity information.
How should Cyclophosphamide monohydrate be handled safely?
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Cyclophosphamide monohydrate is a hazardous substance (Danger, H301, H350). Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., N100 respirator). Ensure adequate ventilation and avoid exposure. Refer to the Safety Data Sheet for full details.
How is Cyclophosphamide monohydrate packed and shipped?
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Cyclophosphamide monohydrate is carefully packed according to international shipping regulations and can be exported globally by Tech Serve Solutions. Specific packaging details are confirmed upon order.
How can I request a sample or quote for Cyclophosphamide monohydrate?
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To request a sample or quote, please contact our sales team through the website or by email, providing your contact details and the quantity required.
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