Cyclothiazide
Cyclothiazide (CAS: 2259-96-3) is a chemical compound with the molecular formula C14H16ClN3O4S2 and a molecular weight of 389.88 g/mol. It functions as an ionotropic glutamate receptor modulator, specifically targeting AMPA/Kainate receptors. This compound is recognised for its role in neuroscience research, contributing to the understanding of excitatory amino acid neurotransmission and ion channel function. Its applications extend to cell biology and signal transduction studies.
- IUPAC
- 6-Chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2-4-benzothiadiazine-7-sulfonamide 1,1-dioxide

Neuroscience Research Tool
Cyclothiazide serves as a valuable tool in neuroscience for modulating ionotropic glutamate receptors, particularly AMPA and kainate types. It aids in investigating neurotransmission processes and understanding the function of ligand-gated ion channels.
Cell Biology Studies
This compound is utilised in cell biology research to explore cellular signalling pathways. Its specific action on ion channels makes it useful for studying cellular responses and physiological mechanisms.
Pharmacological Research
As an approved therapeutic candidate and bioactive small molecule, Cyclothiazide is employed in pharmacological research to investigate its potential therapeutic effects and mechanisms of action.
| Molecular weight | 389.88 |
|---|---|
| Empirical formula | C14H16ClN3O4S2 |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CA1(759), CA4(762), GRIA1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893)rat ... Gria1(50592) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cyclothiazide used for?
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Cyclothiazide is used in neuroscience for modulating ionotropic glutamate receptors (AMPA/Kainate), in cell biology for studying cellular signalling, and in pharmacological research as a bioactive small molecule and potential therapeutic candidate.
What are the CAS number and formula for Cyclothiazide?
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The CAS number for Cyclothiazide is 2259-96-3, and its empirical formula is C14H16ClN3O4S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cyclothiazide (CAS: 2259-96-3) with a specified molecular weight of 389.88. The precise grade and purity are detailed in the product specifications. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should Cyclothiazide be handled safely?
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Cyclothiazide is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Always consult the Safety Data Sheet for comprehensive handling instructions.
Is Cyclothiazide a controlled substance?
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Based on the provided data, Cyclothiazide is not indicated as a controlled substance.
How is Cyclothiazide packed, shipped, and exported?
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Cyclothiazide is typically stored at 2-8°C. Tech Serve Solutions specialises in the global supply and export of fine chemicals, adhering to all necessary regulations for secure and compliant shipping.
How can I request a sample or quote for Cyclothiazide?
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To request a sample or quote for Cyclothiazide (CAS: 2259-96-3), please contact our sales department via the website or direct inquiry, providing your specific requirements.
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