Cyclopentanesulfonyl chloride
Cyclopentanesulfonyl chloride (CAS: 26394-17-2) is an organic sulfur compound with the formula C5H9ClO2S and a molecular weight of 168.64 g/mol. This sulfonyl halide serves as a valuable building block in organic synthesis. It is particularly useful in the preparation of various sulfonamides and sulfonate esters, which are important intermediates in the development of pharmaceuticals and other complex organic molecules. TSS supplies this chemical at a minimum assay of 90%.

Organic Synthesis Intermediate
Cyclopentanesulfonyl chloride is a key reagent in organic chemistry, used for introducing the cyclopentanesulfonyl group into various molecular structures. This is crucial for the synthesis of novel compounds and pharmaceutical candidates.
Pharmaceutical Building Block
The compound is employed in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its reactivity allows for the formation of sulfonamide linkages, a common feature in many drug molecules.
Preparation of Sulfonamides
Reacts readily with amines to form cyclopentanesulfonamides. These derivatives are explored for their potential biological activities and applications in medicinal chemistry.
Synthesis of Sulfonate Esters
This sulfonyl chloride can be converted into cyclopentanesulfonate esters by reaction with alcohols. These esters can serve as leaving groups in further synthetic transformations.
| Molecular weight | 168.64 |
|---|---|
| Empirical formula | C5H9ClO2S |
| Assay | 90% |
| Density | 1.279 g/mL at 25 °C |
| Refractive index | n20/D 1.4918 |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cyclopentanesulfonyl chloride used for?
+
Cyclopentanesulfonyl chloride is primarily used as a building block in organic synthesis, particularly for the preparation of sulfonamides and sulfonate esters, which are often intermediates in pharmaceutical development.
What is the CAS number and formula for Cyclopentanesulfonyl chloride?
+
The CAS number is 26394-17-2 and the empirical formula is C5H9ClO2S.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Cyclopentanesulfonyl chloride with a minimum assay of 90%. We do not represent this product as USP, BP, or EP grade.
How should Cyclopentanesulfonyl chloride be handled safely?
+
Cyclopentanesulfonyl chloride is classified as Danger with H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment including goggles, gloves, and respiratory protection must be worn. Handle in a well-ventilated area and avoid contact with skin, eyes, and clothing.
How is Cyclopentanesulfonyl chloride packed, shipped, and exported?
+
This product is packed in compliance with transport regulations, identified as UN 3265, Class 8, Packing Group II. TSS exports globally, adhering to all international shipping standards for hazardous materials.
How can I request a quote or sample for Cyclopentanesulfonyl chloride?
+
To request a quote or sample, please use the contact form on our website or call our sales department, referencing product CAS number 26394-17-2.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis