Cyclen tetrahydrochloride
Cyclen tetrahydrochloride (CAS: 10045-25-7) is a white to off-white crystalline solid with the molecular formula C8H20N4 · 4HCl and a molecular weight of 318.11 g/mol. It is a derivative of the macrocyclic amine cyclen. This compound serves as a valuable building block in chemical synthesis, particularly for creating complex heterocyclic structures and N-containing molecules. Its well-defined structure makes it useful in research and development settings for novel material and pharmaceutical applications.
- IUPAC
- 1,4,7,10-Tetraazacyclododecane tetrahydrochloride,Cyclen tetrahydrochloride

Organic Synthesis Intermediate
Cyclen tetrahydrochloride is employed as a key intermediate in the synthesis of various organic compounds. Its macrocyclic structure provides a foundation for building more complex molecules with specific functionalities.
Coordination Chemistry
As a macrocyclic ligand precursor, it is utilized in the development of metal complexes. These complexes can find applications in catalysis, sensing, and as models for biological systems.
Materials Science Research
This compound can be incorporated into novel materials, contributing to the development of polymers, supramolecular assemblies, and other advanced materials with tailored properties.
Pharmaceutical Research
Its structure makes it a candidate for use in medicinal chemistry research, where it can be a starting material for developing potential therapeutic agents or diagnostic tools.
| Molecular weight | 318.11 |
|---|---|
| Empirical formula | C8H20N4 · 4HCl |
| Assay | ≥97.0% (N) |
| Melting point | >293 °C (dec.)(lit.)297-300 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cyclen tetrahydrochloride used for?
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Cyclen tetrahydrochloride (CAS: 10045-25-7) is primarily used as a building block in organic synthesis, for coordination chemistry research, in materials science, and in pharmaceutical research.
What are the CAS number and formula for Cyclen tetrahydrochloride?
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The CAS number for Cyclen tetrahydrochloride is 10045-25-7, and its empirical formula is C8H20N4 · 4HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cyclen tetrahydrochloride with an assay of ≥97.0% (N). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the main hazards associated with Cyclen tetrahydrochloride?
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Cyclen tetrahydrochloride is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335).
How is Cyclen tetrahydrochloride handled and shipped?
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Handling requires appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. The product is shipped according to standard chemical handling and transportation regulations. Please consult the SDS for full details.
How can I request a quote or sample for Cyclen tetrahydrochloride?
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To request a quote or sample of Cyclen tetrahydrochloride, please use the contact form on our website or email our sales department with your specific requirements.
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