Cyclen
Cyclen (CAS: 294-90-6), a cyclic tetraamine with the formula C8H20N4, possesses a molecular weight of 172.27 g/mol. This compound is recognised for its ability to form stable complexes with metal ions, making it a valuable chelating agent. It serves as a key building block in supramolecular chemistry and is employed in various chemical synthesis applications, particularly in the development of novel ligands and macrocyclic structures for materials science.
- IUPAC
- 1,4,7,10-Tetraazacyclododecane
- Synonyms
- 1,4,7,10-Tetraazacyclododecane

Chelating Agent
Cyclen is highly effective in coordinating with metal ions, forming stable complexes. This property is exploited in applications requiring selective metal binding and sequestration.
Supramolecular Chemistry
It acts as a fundamental component in the design and synthesis of macrocyclic receptors and host-guest systems due to its unique cyclic tetraamine structure.
Ligand Synthesis
Cyclen is a precursor for the synthesis of more complex polydentate ligands used in catalysis and coordination chemistry research.
Materials Science
Its derivatives are investigated for their potential use in advanced materials, including sensors and ion-recognition systems.
| Molecular weight | 172.27 |
|---|---|
| Empirical formula | C8H20N4 |
| Assay | 97% |
| Melting point | 110-113 °C(lit.) |



Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
- P501Dispose of contents and container per local regulations
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cyclen used for?
+
Cyclen is primarily used as a chelating agent and a building block in supramolecular chemistry and ligand synthesis for materials science applications.
What are the CAS number and formula for Cyclen?
+
The CAS number for Cyclen is 294-90-6, and its chemical formula is C8H20N4.
What grade and purity does Tech Serve Solutions supply for Cyclen?
+
Tech Serve Solutions supplies Cyclen with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should Cyclen be handled safely?
+
Cyclen is classified as dangerous. It is harmful if swallowed and in contact with skin, causes severe skin burns and eye damage, and is toxic to aquatic life with long-lasting effects. Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, must be worn. Ensure adequate ventilation and avoid release to the environment.
Does TSS export Cyclen?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Cyclen.
How can I request a quote or sample for Cyclen?
+
To request a quote or sample for Cyclen, please contact our sales team via the website or phone.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis