CK-666
CK-666 (CAS 442633-00-3), with the molecular formula C18H17FN2O and a molecular weight of 296.34 g/mol, is a chemical compound used in biological research. It functions as an inhibitor, specifically targeting Arp2/3 complex-mediated actin nucleation. This makes it a valuable tool for investigating cellular structural dynamics and the cytoskeleton. Supplied by Tech Serve Solutions, it is available for research purposes.
- IUPAC
- 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]-benzamide,CK 666,CK-0944666
- Synonyms
- 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]-benzamide,CK 666,CK-0944666
Investigation of Actin Nucleation
CK-666 is employed to study the Arp2/3 complex, a key regulator of actin cytoskeleton formation. Its inhibitory action allows researchers to dissect the roles of Arp2/3-mediated actin nucleation in various cellular processes.
Cellular Structural Dynamics Research
By inhibiting actin polymerization pathways controlled by the Arp2/3 complex, CK-666 aids in understanding cellular structural changes, cell motility, and intracellular transport mechanisms.
Cytoskeleton Research
This compound serves as a probe to investigate the dynamic organisation of the actin cytoskeleton, crucial for cell shape, division, and migration.
| Molecular weight | 296.34 |
|---|---|
| Empirical formula | C18H17FN2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to tan |
| Solubility | DMSO: ≥25 mg/mL |
| Storage temperature | 2-8°C |
| Application | CK-666 may be used to study Arp2/3-mediated structural changes in cells. |
Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is CK-666 used for?
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CK-666 is primarily used in research to inhibit Arp2/3-mediated actin nucleation, allowing for the study of cellular structural dynamics and the cytoskeleton.
What are the CAS number and formula for CK-666?
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The CAS number for CK-666 is 442633-00-3, and its empirical formula is C18H17FN2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies CK-666 with a minimum purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should CK-666 be handled?
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CK-666 is classified as a Warning with hazard statement H319 (Causes serious eye irritation). When handling, wear protective gloves and eye protection. In case of contact with eyes, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do. P305 + P351 + P338.
How is CK-666 packed, shipped, and exported?
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CK-666 is typically supplied as a white to tan powder. Tech Serve Solutions, as a global supplier, handles the packing, shipping, and export of chemicals in compliance with relevant regulations.
How can I request a quote or sample of CK-666?
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To request a quote or a sample of CK-666, please contact our sales team through the Tech Serve Solutions website or by phone.
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