CKI-7 dihydrochloride
CKI-7 dihydrochloride (CAS: 1177141-67-1) is a chemical compound with the formula C11H12ClN3O2S · 2HCl and a molecular weight of 358.67 g/mol. It presents as a white to light tan solid. This compound is primarily utilised in research settings as a selective inhibitor, particularly within the fields of cell biology and signalling, acting on casein kinases.
- IUPAC
- N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride
Biochemical Research
CKI-7 dihydrochloride serves as a valuable tool in biochemical research, particularly for studying the roles of casein kinases (CKs) and glycogen synthase kinases (GSKs). Its inhibitory properties allow for the investigation of cellular pathways involving these enzymes.
Cell Biology Studies
In cell biology, this compound is employed to explore cellular processes regulated by serine/threonine kinases. Researchers use it to understand signal transduction pathways and their impact on cell behaviour and function.
Neuroscience Research
CKI-7 dihydrochloride finds application in neuroscience research, aiding in the study of cell signalling mechanisms relevant to neuronal function and disease.
| Molecular weight | 358.67 |
|---|---|
| Empirical formula | C11H12ClN3O2S · 2HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to light tan |
| Solubility | H2O: >5 mg/mL |
| Storage temperature | −20°C |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is CKI-7 dihydrochloride used for?
+
CKI-7 dihydrochloride is primarily used as a research tool in biochemistry and cell biology, particularly for investigating the function of casein kinases (CKs) and glycogen synthase kinases (GSKs) and their roles in cell signalling pathways. It is also used in neuroscience research.
What are the CAS number and formula for CKI-7 dihydrochloride?
+
The CAS number for CKI-7 dihydrochloride is 1177141-67-1, and its empirical formula is C11H12ClN3O2S · 2HCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies CKI-7 dihydrochloride with an assay of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.
How should CKI-7 dihydrochloride be handled safely?
+
CKI-7 dihydrochloride is classified as acutely toxic (Danger, H301). Handle with appropriate personal protective equipment including eyeshields, faceshields, gloves, and a type P2 respirator. Ensure handling occurs in a well-ventilated area. Refer to the Safety Data Sheet for full details.
How is CKI-7 dihydrochloride packaged and exported?
+
CKI-7 dihydrochloride is supplied as a solid, stored desiccated at -20°C. As a global supplier, Tech Serve Solutions has extensive experience in exporting chemicals worldwide, adhering to all relevant shipping and customs regulations.
How can I request a sample or quote for CKI-7 dihydrochloride?
+
To request a sample or a quote for CKI-7 dihydrochloride, please contact our sales team through the dedicated inquiry form on our website or via direct email, providing your contact details and the quantity required.
▶ Related products
(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology
(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis