Guanosine 5′-diphospho-D-mannose sodium salt from Saccharomyces cerevisiae
Guanosine 5′-diphospho-D-mannose sodium salt (CAS: 103301-73-1) is a vital nucleotide sugar with the molecular formula C16H23N5O16P2Na2. Sourced from Saccharomyces cerevisiae, this compound serves as a critical substrate for mannosylation reactions catalysed by mannosyltransferases. It is instrumental in studying mannose metabolism, cellular transport mechanisms, and its role within the sugar nucleotide pools of various cell types, including its function as a precursor in plant ascorbic acid biosynthesis.
- IUPAC
- GDP-Man,GDP-mannose
Glycosyltransferase Substrate
Guanosine diphosphate mannose (GDP-mannose) acts as a direct substrate for mannosyltransferases, facilitating the enzymatic addition of mannose residues in glycosylation pathways. This is crucial for the synthesis of complex glycans and glycoproteins in various biological systems.
Metabolic Pathway Research
This compound is employed in the investigation of mannose metabolism and related biochemical pathways. Researchers utilise it to understand the dynamics of sugar nucleotide pools and their influence on cellular processes and signalling.
Cellular Sugar Nucleotide Pool Studies
GDP-mannose is utilized to study its transport across cellular membranes and its contribution to the intracellular pool of nucleotide sugars. This is important for understanding cellular energy and biosynthetic capacity.
Ascorbic Acid Biosynthesis
In plant systems, GDP-mannose serves as a precursor in the biosynthesis of L-ascorbic acid (Vitamin C). Research in this area investigates the enzymatic steps and regulation of this important plant metabolic pathway.
| Molecular weight | 649.30 |
|---|---|
| Linear formula | C16H23N5O16P2Na2 |
| Assay | ≥97% (HPLC) |
| Storage temperature | −20°C |
| Application | Guanosine diphosphate mannose (GDP-mannose) is a nucleotide sugar substrate for glycosyltransferase (mannosylation) reactions mediated by mannosyltransferases. GDP-mannose may be used to study its transport, mannose metabolism, and presence as a component of the sugar nucleotide pools of various cell types. GDP-mannose is used as a precursor of L-ascorbic acid in plants. |
| Type | Type I |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Guanosine 5′-diphospho-D-mannose sodium salt used for?
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Guanosine 5′-diphospho-D-mannose sodium salt is used as a substrate for glycosyltransferase (mannosylation) reactions, in studies of mannose metabolism and transport, and as a precursor of L-ascorbic acid in plants.
What is the CAS number and formula for Guanosine 5′-diphospho-D-mannose sodium salt?
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The CAS number is 103301-73-1 and the molecular formula is C16H23N5O16P2Na2.
What grade and purity does Tech Serve Solutions supply for Guanosine 5′-diphospho-D-mannose sodium salt?
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Tech Serve Solutions supplies Guanosine 5′-diphospho-D-mannose sodium salt with an assay of ≥97% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling considerations for Guanosine 5′-diphospho-D-mannose sodium salt?
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This product is classified under WGK Germany 3, indicating a high hazard to water. Handle with appropriate personal protective equipment in a well-ventilated area. Consult the Safety Data Sheet for detailed handling and disposal information.
How is Guanosine 5′-diphospho-D-mannose sodium salt shipped and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, including Guanosine 5′-diphospho-D-mannose sodium salt, ensuring appropriate packaging and documentation for international transit. Shipping is typically conducted at -20°C.
How can I request a quote or sample for Guanosine 5′-diphospho-D-mannose sodium salt?
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To request a quote or a sample of Guanosine 5′-diphospho-D-mannose sodium salt, please contact our sales team through the TSS website or by phone, providing your specific requirements.
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