Guanosine 5′-[β,γ-imido]triphosphate trisodium salt hydrate
Guanosine 5′-[β,γ-imido]triphosphate trisodium salt hydrate (CAS: 148892-91-5) is a non-hydrolyzable analog of GTP, crucial in biochemical research. With a molecular weight of 588.14 (anhydrous basis) and identified by the empirical formula C10H14N6Na3O13P3 · xH2O, it serves as a preferred analogue for activating ADP-ribosylation factors. This white powder, shipped in dry ice, is supplied by Tech Serve Solutions for advanced research applications.
- IUPAC
- β:γ-Imidoguanosine 5′-triphosphate trisodium salt hydrate,5′-Guanylyl-imidodiphosphate trisodium salt hydrate,GMP-PNP,Gpp(NH)p
- Synonyms
- β:γ-Imidoguanosine 5′-triphosphate trisodium salt hydrate5′-Guanylyl-imidodiphosphate trisodium salt hydrateGMP-PNPGpp(NH)p
![Guanosine 5′-[β,γ-imido]triphosphate trisodium salt hydrate (C10H14N6Na3O13P3 · xH2O) — chemical structure, CAS 148892-91-5; Life Science, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F148892-91-5.png&w=3840&q=75)
GTP Analogue in Biochemical Research
Serves as a non-hydrolyzable analogue of Guanosine triphosphate (GTP), enabling stable biochemical assays and mechanistic studies where GTP hydrolysis needs to be bypassed.
ADP-Ribosylation Factor Activation
This compound is the preferred GTP analogue for activating ADP-ribosylation factors (ARFs), playing a key role in studies of protein trafficking and cellular signalling pathways.
Cell Signaling and Neuroscience Studies
Utilised in research investigating G-protein coupled receptors (GPCRs) and other signalling cascades where GTP binding and hydrolysis are critical regulatory steps.
| Molecular weight | 588.14 (anhydrous basis) |
|---|---|
| Empirical formula | C10H14N6Na3O13P3 · xH2O |
| Assay | ≥85% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | H2O: soluble50 mg/mL |
| Storage temperature | −20°C |
| Application | Non-hydrolyzable analog of GTP; the preferred GTP analog to activate ADP-ribosylation factor. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | dry ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Guanosine 5′-[β,γ-imido]triphosphate trisodium salt hydrate used for?
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This compound is a non-hydrolyzable analogue of GTP, primarily used to activate ADP-ribosylation factors and in biochemical research requiring stable GTP analogues for mechanistic studies.
What are the CAS number and formula for this product?
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The CAS number is 148892-91-5, and the empirical formula is C10H14N6Na3O13P3 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥85% (HPLC). It is not supplied as USP, EP, or BP grade, and TSS does not represent it as such.
What are the safety and handling considerations for this chemical?
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This product is classified as a Warning with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves should be used. Handle in a well-ventilated area.
How is this chemical shipped and exported?
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Guanosine 5′-[β,γ-imido]triphosphate trisodium salt hydrate is shipped in dry ice to maintain its stability during transit. TSS is a specialist global supplier and exporter.
How can I request a quote or sample?
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Please contact our sales team via the website or your account manager to request a quote or a sample of Guanosine 5′-[β,γ-imido]triphosphate trisodium salt hydrate.
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