Chlorodiphenylsilane
Chlorodiphenylsilane (CAS: 1631-83-0) is an organosilicon compound with the linear formula (C6H5)2SiHCl and a molecular weight of 218.75 g/mol. This substance functions as a valuable reagent in chemical synthesis, particularly in the field of silicon-based chemistry. It is primarily employed for protection and derivatization reactions, offering a reliable method for modifying organic molecules. Its reactivity makes it a key intermediate in various synthetic pathways.
- IUPAC
- Diphenylchlorosilane
- Synonyms
- Diphenylchlorosilane

Protecting Group Chemistry
Chlorodiphenylsilane is utilised as a reagent for introducing protecting groups onto hydroxyl and amino functionalities. This enables selective reactions elsewhere in a molecule by temporarily masking reactive sites.
Derivatization Agent
It serves as a derivatizing agent in analytical chemistry, particularly for gas chromatography. Converting polar compounds into less polar, more volatile derivatives can improve separation and detection.
Silicon-Based Synthesis
As a silicon-containing compound, it is an important building block in the synthesis of organosilicon polymers and materials. Its structure allows for incorporation into polymer backbones or side chains.
Organic Synthesis Intermediate
Chlorodiphenylsilane acts as an intermediate in the synthesis of more complex organic molecules. The reactive Si-Cl bond can be readily displaced by various nucleophiles.
| Molecular weight | 218.75 |
|---|---|
| Linear formula | (C6H5)2SiHCl |
| Assay | 90% |
| Boiling point | 143 °C/10 mmHg(lit.) |
| Density | 1.118 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.578(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | 105 °C / 221 °F |
|---|---|
| Transport (UN / ADR) | UN 2987 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chlorodiphenylsilane used for?
+
Chlorodiphenylsilane is used in chemical synthesis as a protecting and derivatizing reagent, particularly in silicon-based chemistry and organic synthesis.
What is the CAS number and formula for Chlorodiphenylsilane?
+
The CAS number for Chlorodiphenylsilane is 1631-83-0, and its linear formula is (C6H5)2SiHCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Chlorodiphenylsilane with a minimum assay of 90%. We do not represent this product as USP, BP, or EP grade.
How should Chlorodiphenylsilane be handled safely?
+
Chlorodiphenylsilane is a corrosive substance that reacts violently with water. Handle with extreme care, wearing appropriate personal protective equipment including gloves, eye protection, and protective clothing. Ensure adequate ventilation and avoid contact with moisture. Refer to the Safety Data Sheet for full handling precautions.
How is Chlorodiphenylsilane packed and exported?
+
Chlorodiphenylsilane is packed and exported in compliance with international transport regulations for hazardous materials, including UN 2987 classification.
How can I request a quote or sample for Chlorodiphenylsilane?
+
To request a quote or sample for Chlorodiphenylsilane, please contact our sales team via the website or direct inquiry.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis