Chlorobis(4-fluorophenyl)methane
Chlorobis(4-fluorophenyl)methane (CAS: 27064-94-4) is an organofluorine compound with the molecular formula (FC₆H₄)₂CHCl and a molecular weight of 238.66 g/mol. This chemical serves as a valuable building block in organic synthesis, particularly for introducing difluorobenzhydryl moieties into more complex molecular structures. Its properties make it useful in the development of novel compounds across various research and industrial sectors.
- IUPAC
- 4,4′-Difluorobenzhydryl chloride
- Synonyms
- 4,4′-Difluorobenzhydryl chloride

Organic Synthesis Intermediate
Chlorobis(4-fluorophenyl)methane is utilized as a key intermediate in the synthesis of diverse organic molecules. Its reactive chlorine atom allows for facile substitution reactions, enabling the construction of complex fluorinated aromatic compounds.
Fluorinated Building Block
As a specialized fluorinated building block, this compound is instrumental in medicinal chemistry and materials science research. It facilitates the incorporation of fluorine atoms, which can significantly alter the physicochemical and biological properties of target molecules.
Research and Development
The compound finds application in academic and industrial R&D settings for exploring new chemical entities and reaction pathways. Its unique structure makes it a candidate for use in the synthesis of novel pharmaceuticals or agrochemicals.
| Molecular weight | 238.66 |
|---|---|
| Linear formula | (FC6H4)2CHCl |
| Assay | 97% |
| Boiling point | 126-128 °C/1 mmHg(lit.) |
| Density | 1.28 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.557(lit.) |


Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chlorobis(4-fluorophenyl)methane used for?
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Chlorobis(4-fluorophenyl)methane is primarily used as an intermediate in organic synthesis and as a fluorinated building block for research and development in areas such as medicinal chemistry and materials science.
What are the CAS number and chemical formula for Chlorobis(4-fluorophenyl)methane?
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The CAS number is 27064-94-4, and the linear chemical formula is (FC₆H₄)₂CHCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chlorobis(4-fluorophenyl)methane with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary hazards associated with Chlorobis(4-fluorophenyl)methane?
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Chlorobis(4-fluorophenyl)methane is classified as Danger, with hazards H314 (Causes severe skin burns and eye damage) and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including chemical-resistant gloves, eye protection, and respiratory protection, should be used when handling this substance.
How is Chlorobis(4-fluorophenyl)methane packed, shipped, and exported?
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This product is packed and shipped in compliance with UN 3265, Hazard Class 8, Packing Group II regulations for corrosive liquid, acidic, organic, n.o.s. Tech Serve Solutions exports fine chemicals globally.
How can I request a quote or sample for Chlorobis(4-fluorophenyl)methane?
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To request a quote or sample, please contact our sales department through the website or by phone, providing the product name and CAS number (27064-94-4).
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