Chlorhexidine dihydrochloride
Chlorhexidine dihydrochloride (CAS: 3697-42-5; Formula: C22H30Cl2N10 · 2HCl; MW: 578.37) is a potent organic compound widely recognised for its antiseptic and disinfectant properties. It functions by disrupting bacterial cell membranes, leading to cell death. This efficacy makes it a valuable component in various formulations aimed at preventing microbial growth and infection control in diverse settings, including healthcare and personal care products.
- IUPAC
- 1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane; 1,1′-Hexamethylenebis(5-[p-chlorophenyl]biguanide),Lisium

Antiseptic Formulations
Utilised in the preparation of antiseptic solutions and washes for skin and wound disinfection. Its broad-spectrum antimicrobial activity helps to reduce microbial load on surfaces and in biological systems.
Disinfectant Products
Incorporated into disinfectant formulations for hard surfaces and medical equipment. This application leverages its ability to inactivate a wide range of bacteria, fungi, and some viruses.
Pharmaceutical Intermediates
Serves as a key intermediate in the synthesis of more complex pharmaceutical agents. Its chemical structure allows for further functionalisation in organic synthesis pathways.
Research and Development
Employed in research laboratories as a reagent for antimicrobial studies and chemical synthesis. Its well-defined properties make it a reliable compound for scientific investigations.
| Molecular weight | 578.37 |
|---|---|
| Empirical formula | C22H30Cl2N10 · 2HCl |
| Assay | ≥98% |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chlorhexidine dihydrochloride used for?
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Chlorhexidine dihydrochloride is primarily used as an antiseptic and disinfectant due to its broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses. It is found in formulations for skin and wound care, as well as for disinfecting surfaces and medical equipment. It also functions as an intermediate in chemical synthesis and in research applications.
What is the CAS number and formula for Chlorhexidine dihydrochloride?
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The CAS number for Chlorhexidine dihydrochloride is 3697-42-5, and its molecular formula is C22H30Cl2N10 · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chlorhexidine dihydrochloride with an assay of ≥98%. We do not represent this product as USP, BP, or EP grade unless explicitly stated otherwise in the product specifications.
How should Chlorhexidine dihydrochloride be handled safely?
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Chlorhexidine dihydrochloride can cause skin irritation, serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation, avoid breathing dust, and wash hands thoroughly after handling. Store at 2-8°C.
Is Chlorhexidine dihydrochloride a controlled substance?
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Based on the provided data, Chlorhexidine dihydrochloride is not listed as a controlled substance. However, regulations can vary by jurisdiction.
How are Tech Serve Solutions products packed and shipped?
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Tech Serve Solutions professionally packs and ships fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all necessary safety and regulatory standards for export.
How can I request a sample or quote for Chlorhexidine dihydrochloride?
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To request a sample or a quote for Chlorhexidine dihydrochloride, please contact our sales team through the website or via the provided contact details.
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