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Chlorhexidine

CAS 55-56-1[-(CH2)3NHC(=NH)NHC(=NH)NHC6H4Cl]2Chemical Synthesis

Chlorhexidine (CAS: 55-56-1) is an organic compound with the molecular formula [-(CH2)3NHC(=NH)NHC(=NH)NHC6H4Cl]2 and a molecular weight of 505.45 g/mol. It functions as a potent antibacterial agent. Its primary applications include use in oral antiseptics and the development of specialized coatings and nanoparticles for dental hygiene and medical treatments.

IUPAC
1,1′-Hexamethylenebis[5-(4-chlorophenyl)biguanide]
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Chlorhexidine ([-(CH2)3NHC(=NH)NHC(=NH)NHC6H4Cl]2) — chemical structure, CAS 55-56-1; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisGuanidinesNitrogen CompoundsOrganic Building Blocks
01 /Applications

Oral Antiseptic

Chlorhexidine is widely recognised as a gold standard for oral antiseptics. It is employed in various formulations designed for mouth rinses and dental care products to maintain oral hygiene.

Surgical Suture Coatings

The compound has been utilised in optimising novel slow-release chlorhexidine coatings for surgical sutures. This application aims to enhance post-operative care and prevent infection.

Dental Nanoparticles

Chlorhexidine has been incorporated into functionalized calcium phosphate nanoparticles. These nanoparticles are valuable for developing advanced materials for oral hygiene and dental treatments.

02 /Properties
Molecular weight505.45
Linear formula[-(CH2)3NHC(=NH)NHC(=NH)NHC6H4Cl]2
Assay≥99.0% (HPLC)
ApplicationChlorhexidine, the "gold standard" in oral antiseptics, has been used to optimize novel slow release chlorhexidine coatings based on fatty acids in surgical sutures1. Chlorhexidine, antibacterial agent, has been used in preparaing chlorhexidine-functionalized calcium phosphate nanoparticles, useful for oral hygiene and dental treatment2.
Melting point134-136 °C(lit.)134-136 °C
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
GHS hazard pictogram: Health hazard (GHS08)
Health hazard
GHS hazard pictogram: Environmental hazard (GHS09)
Environmental hazard
Danger

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H334May cause allergy or asthma symptoms if inhaled
  • H335May cause respiratory irritation
  • H410Very toxic to aquatic life with long-lasting effects

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P273Avoid release to the environment
  • P305IF IN EYES
  • P342
  • P501Dispose of contents and container per local regulations
Protective equipmentdust mask type N95 (US), Eyeshields, Faceshields, Gloves
Transport (UN / ADR)UN 3077 9 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi,N
Risk statements (R)36/37/38-43-50/53
Safety statements (S)26-36/37-60-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
55-56-1
MDL number
MFCD00009673
PubChem substance
24857031
Beilstein registry
2826432
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Chlorhexidine used for?

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Chlorhexidine is primarily used as an antibacterial agent, particularly as a gold standard in oral antiseptics. It is also applied in developing slow-release coatings for surgical sutures and functionalized nanoparticles for dental care.

What is the CAS number and chemical formula for Chlorhexidine?

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The CAS number for Chlorhexidine is 55-56-1, and its linear formula is [-(CH2)3NHC(=NH)NHC(=NH)NHC6H4Cl]2.

What grade and purity does Tech Serve Solutions supply for Chlorhexidine?

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Tech Serve Solutions supplies Chlorhexidine with an assay of ≥99.0% (HPLC). We do not represent this product as USP, BP, or EP grade unless explicitly stated in the product specifications.

What are the safety considerations when handling Chlorhexidine?

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Chlorhexidine is classified with danger signal words and carries hazard statements including H315 (Causes skin irritation), H319 (Causes serious eye irritation), H334 (May cause allergy or asthma symptoms or breathing difficulties if inhaled), H335 (May cause respiratory irritation), and H410 (Very toxic to aquatic life with long lasting effects). Appropriate personal protective equipment includes a dust mask type N95, eyeshields, faceshields, and gloves.

How is Chlorhexidine packaged, shipped, and exported?

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Chlorhexidine is packaged according to industry standards for chemical safety and stability. Tech Serve Solutions is experienced in exporting chemicals globally, adhering to all relevant shipping regulations, including UN 3077 9 / PGIII classification.

How can I request a sample or quote for Chlorhexidine?

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To request a sample or a quote for Chlorhexidine, please contact our sales team through the details provided on the Tech Serve Solutions website.

Need Chlorhexidine in a specific grade or volume?