Butyl chloroformate
Butyl chloroformate (CAS 592-34-7), with the linear formula ClCOOCH2CH2CH2CH3 and a molecular weight of 136.58 g/mol, is a reactive organic compound. It serves as a valuable building block and carbonyl compound in chemical synthesis. Primarily used in organic chemistry for derivatization and as an intermediate in the production of various complex molecules, including pharmaceuticals and polymers. This compound requires careful handling due to its hazardous properties.
Synthesis of Dextran Alkyl Carbonates
Butyl chloroformate is employed as a key reagent in the synthesis of dextran alkyl carbonates, a class of modified polysaccharides with potential applications in various fields.
Radical Polymerization Agents
It participates in the synthesis of specific ditthiocarbamate compounds that function as radical polymerization agents with reversible addition-fragmentation chain transfer (RAFT) capabilities.
Derivatization Reagent
Butyl chloroformate is utilised as a derivatization reagent for the determination of linsidomine in plasma, facilitating its detection via high-performance liquid chromatography coupled with tandem mass spectrometry.
| Molecular weight | 136.58 |
|---|---|
| Linear formula | ClCOOCH2CH2CH2CH3 |
| Assay | ≥97.0% (GC) |
| Boiling point | 142 °C(lit.) |
| Density | 1.057 g/mL at 20 °C1.074 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.412(lit.)n20/D 1.413 |
| Vapour pressure | 2.42 psi (20 °C) |
| Storage temperature | 2-8°C |
| Application | • Butyl chloroformate was used in the synthesis of dextran alkyl carbonates1. • It was also used in the synthesis of S-tert-alkyl-N,N-alkoxycarbonylmethyl-dithiocarbamate, radical polymerization with reversible addition-fragmentation chain transfer agent2. • It was used as derivatization reagent in determination of linsidomine in plasma using high-performance liquid chromatographic separation with tandem mass spectrometric detection3. |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 38 °C / 100.4 °F |
| Transport (UN / ADR) | UN 2743 6.1/PG 2 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T |
| Risk statements (R) | 10-23-34 |
| Safety statements (S) | 26-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Butyl chloroformate used for?
+
Butyl chloroformate is used in chemical synthesis as a building block, for derivatization, and in the preparation of dextran alkyl carbonates and specific radical polymerization agents.
What is the CAS number and formula for Butyl chloroformate?
+
The CAS number for Butyl chloroformate is 592-34-7 and its linear formula is ClCOOCH2CH2CH2CH3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Butyl chloroformate with an assay of ≥97.0% (GC). We do not represent this product as USP, BP, or EP grade.
How should Butyl chloroformate be handled safely?
+
Butyl chloroformate is a Danger hazard (GHS02, GHS05, GHS06) with H-statements H226-H314-H331. It is flammable and causes severe skin burns and eye damage, and is toxic if inhaled. Handle with appropriate personal protective equipment including faceshields, chemical-resistant gloves, and respiratory protection in a well-ventilated area.
How is Butyl chloroformate packed, shipped, and exported?
+
Butyl chloroformate is available from Tech Serve Solutions and is exported globally. Specific packaging and shipping details are available upon request and comply with all relevant transport regulations.
How can I request a sample or quote for Butyl chloroformate?
+
To request a sample or a quote for Butyl chloroformate, please contact our sales team through the website or by phone, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis