Bufalin
Bufalin (CAS: 465-21-4), with the molecular formula C24H34O4 and a molecular weight of 386.52 g/mol, is a bufadienolide steroid. This compound is recognised for its potent biological activities, particularly as an apoptosis inducer. It finds utility in research settings, specifically within cell biology and cancer research, for investigating cellular death pathways and signalling mechanisms. Bufalin is also studied for its presence in traditional medicine.
- IUPAC
- 3β,14-Dihydroxy-5β,20(22)-bufadienolide,5β,20(22)-Bufadienolide-3β,14-diol
Apoptosis Research
Bufalin is widely employed as a research tool to study the mechanisms of programmed cell death (apoptosis). It can induce apoptosis in various cell lines, making it valuable for understanding cellular signalling pathways.
Cell Biology Studies
This compound is utilized in cell biology research to investigate cellular processes, including cell cycle regulation and signalling cascades. Its effects on cell proliferation and survival are subjects of ongoing study.
Cancer Research
As an apoptosis inducer, Bufalin is investigated for its potential in cancer research. Studies explore its effects on cancer cell growth and its possible therapeutic applications in oncology.
Traditional Medicine Research
Bufalin is a component found in traditional Chinese medicine. Research aims to elucidate its pharmacological properties and understand its historical uses in herbal remedies.
| Molecular weight | 386.52 |
|---|---|
| Empirical formula | C24H34O4 |
| Storage temperature | 2-8°C |
Hazard statements
- H300Fatal if swallowed
Precautionary statements
- P264Wash thoroughly after handling
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3462 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 28 |
| Safety statements (S) | 28-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bufalin used for?
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Bufalin is used in research for studying apoptosis, cell biology, cancer, and traditional medicine. It is known for its ability to induce programmed cell death in experimental settings.
What are the CAS number and formula for Bufalin?
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Bufalin has the CAS number 465-21-4 and the molecular formula C24H34O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bufalin typically as a research-grade chemical with high purity. Specific assay details are available on the Certificate of Analysis provided with each batch. We do not represent this product as USP, BP, EP, or any other pharmacopoeial standard unless explicitly stated.
How should Bufalin be handled safely?
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Bufalin is classified as acutely toxic (Danger, H300). Handling requires stringent safety precautions, including the use of approved respiratory protection (N100 or P3 filters), protective gloves, and eye/face protection (eyeshields, faceshields). Strict adherence to P264 and P301 + P310 precautionary statements is essential.
Is Bufalin a controlled substance?
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The provided data does not indicate that Bufalin is a scheduled or controlled substance. However, users should always verify local regulations.
How is Bufalin shipped and exported?
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Bufalin is classified under UN 3462, Class 6.1, Packing Group II, for transportation. Tech Serve Solutions is experienced in exporting chemicals globally, ensuring compliance with all relevant shipping and customs regulations.
How can I request a quote or sample for Bufalin?
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To request a quote or a sample of Bufalin, please contact our sales team through the website or by phone. Provide the product name (Bufalin) and CAS number (465-21-4) for efficient processing.
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