Bumetanide
Bumetanide (CAS 28395-03-1) is a potent loop diuretic with the chemical formula C17H20N2O5S and a molecular weight of 364.42 g/mol. It functions by inhibiting the Na+-K+-2Cl- symporter in the thick ascending limb of the loop of Henle. This action leads to increased excretion of water, sodium, chloride, potassium, and other electrolytes. Bumetanide is primarily used to manage edema associated with congestive heart failure, liver disease, and renal disease.
- IUPAC
- 3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid
Diuretic Therapy
Bumetanide is a powerful loop diuretic prescribed for the management of edema. Its efficacy stems from its action on the renal tubules, promoting significant diuresis.
Edema Management
It is clinically used to reduce fluid accumulation (edema) in patients suffering from conditions such as chronic heart failure, liver cirrhosis, and kidney disorders.
Research Chemical
As a bioactive small molecule, Bumetanide is utilised in pharmacological research to study ion transport mechanisms and related physiological processes.
| Molecular weight | 364.42 |
|---|---|
| Empirical formula | C17H20N2O5S |
| Assay | ≥98% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bumetanide used for?
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Bumetanide is primarily used as a loop diuretic to treat edema associated with congestive heart failure, liver disease, and kidney disorders. It is also used in scientific research to investigate ion channels and cellular signaling.
What is the CAS number and chemical formula for Bumetanide?
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The CAS number for Bumetanide is 28395-03-1, and its chemical formula is C17H20N2O5S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bumetanide with a purity of ≥98%. We do not represent this product as USP, BP, or EP grade unless explicitly stated in the product specifications.
What are the safety precautions when handling Bumetanide?
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When handling Bumetanide, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if there is a risk of dust inhalation. Refer to the safety data sheet for full handling instructions.
How is Bumetanide packed, shipped, and exported?
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Bumetanide is carefully packed to ensure product integrity during transit. Tech Serve Solutions is experienced in exporting chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for Bumetanide?
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To request a sample or a quotation for Bumetanide, please contact our sales team through the website or by phone, providing your specific requirements.
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