Butenafine hydrochloride
Butenafine hydrochloride (CAS: 101827-46-7), with the empirical formula C23H27N · HCl and a molecular weight of 353.93 g/mol, is a synthetic benzylamine derivative. It presents as a white to off-white powder. Primarily recognised for its antifungal properties, butenafine hydrochloride is an active pharmaceutical ingredient used in topical dermatological preparations for the treatment of superficial fungal infections. It is a valuable compound for pharmaceutical research and development.
- IUPAC
- N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamine hydrochloride,Butenafine hydrochloride,Mentax,N-[[4-(1,1-Dimethylethyl)phenyl]methyl]-N-methyl-1-naphthalenemethanamine hydrochloride
- Synonyms
- N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamine hydrochlorideN-"[[4-(1,1-Dimethylethyl)phenyl]methyl]-N-methyl-1-naphthalenemethanamine hydrochloride
Antifungal Agent
Butenafine hydrochloride is an established active pharmaceutical ingredient (API) utilised in the formulation of topical antifungal medications. It effectively treats various superficial mycoses.
Dermatological Therapeutics
Its specific application is in treating skin fungal infections, including tinea pedis (athlete's foot), tinea corporis (ringworm), and tinea cruris (jock itch). It is formulated into creams and solutions.
Pharmaceutical Research
As a well-characterised compound, butenafine hydrochloride serves as a reference standard and a subject of study in drug discovery and development programs investigating novel antifungal agents or therapeutic delivery systems.
| Molecular weight | 353.93 |
|---|---|
| Empirical formula | C23H27N · HCl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to off-white |
| Solubility | DMSO: ≥10 mg/mL |
| Storage temperature | room temp |
Hazard statements
- H312Harmful in contact with skin
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Water hazard class (WGK, DE) | nwg |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 21 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Butenafine hydrochloride used for?
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Butenafine hydrochloride is primarily used as an active pharmaceutical ingredient in topical antifungal medications to treat superficial fungal skin infections.
What are the CAS number and formula for Butenafine hydrochloride?
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The CAS number for Butenafine hydrochloride is 101827-46-7, and its empirical formula is C23H27N · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Butenafine hydrochloride with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade unless explicitly stated otherwise.
What are the safety considerations when handling Butenafine hydrochloride?
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Butenafine hydrochloride is classified as a GHS07 Warning substance, with hazard statement H312 (Harmful in contact with skin). Appropriate personal protective equipment (P280) should be worn to avoid skin contact.
How is Butenafine hydrochloride shipped?
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Butenafine hydrochloride is typically stored at room temperature and can be shipped internationally. Please contact us for specific export details and packaging options.
How can I request a sample or quote?
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To request a sample or a quotation for Butenafine hydrochloride, please use the contact form on our website or call our sales department directly.
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