Butyrylhydroxamic acid
Butyrylhydroxamic acid (CAS: 4312-91-8), with the molecular formula C4H9NO2 and a molecular weight of 103.12 g/mol, is a white to tan powder. It functions as a potent inhibitor of histone deacetylases (HDACs), playing a crucial role in gene regulation. This compound is valuable in biochemical research, particularly in studies involving cell biology, cell signaling, and neuroscience, where it aids in understanding epigenetic mechanisms.
- IUPAC
- N-hydroxybutanamide
- Synonyms
- N-hydroxybutanamide

Histone Deacetylase (HDAC) Inhibition
Butyrylhydroxamic acid serves as a research tool to inhibit histone deacetylase activity. This inhibition leads to the accumulation of acetylated histones, impacting gene expression and cellular processes. It is used to study the epigenetic mechanisms underlying various biological functions.
Cell Biology Research
As a bioactive small molecule, this compound is utilized in cell biology studies to investigate cellular responses to altered gene expression. Its ability to modulate epigenetic marks makes it useful for examining DNA-RNA transcription and gene regulation.
Neuroscience and Cell Signaling
This hydroxamic acid derivative finds application in neuroscience and cell signaling research. It helps scientists explore the roles of HDACs in neuronal function and intracellular communication pathways.
| Molecular weight | 103.12 |
|---|---|
| Empirical formula | C4H9NO2 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to tan |
| Solubility | H2O: ≥25 mg/mL |
| Storage temperature | −20°C |

Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | wet ice |
|---|---|
| Storage Condition | desiccated |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Butyrylhydroxamic acid used for?
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Butyrylhydroxamic acid (CAS: 4312-91-8) is used in biochemical research as an inhibitor of histone deacetylases (HDACs), playing a role in studies of gene regulation, cell biology, cell signaling, and neuroscience.
What is the CAS number and molecular formula for Butyrylhydroxamic acid?
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The CAS number is 4312-91-8, and the molecular formula is C4H9NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Butyrylhydroxamic acid with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Butyrylhydroxamic acid be handled?
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Butyrylhydroxamic acid is classified as a GHS07 (Warning) substance and carries the hazard statement H302 (Harmful if swallowed). Handle with appropriate personal protective equipment in a well-ventilated area to avoid ingestion.
How is Butyrylhydroxamic acid shipped?
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Butyrylhydroxamic acid is shipped on wet ice and should be stored under desiccated conditions at -20°C.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team through the TSS website or by telephone.
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