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Bromoacetyl chloride

CAS 22118-09-8BrCH2COClChemical Synthesis

Bromoacetyl chloride (CAS 22118-09-8) is a reactive organic compound with the linear formula BrCH₂COCl and a molecular weight of 157.39 g/mol. As an acid halide and carbonyl compound, it serves as a valuable building block in organic synthesis. It is commonly employed in the chemical industry for the introduction of the bromoacetyl group into various molecules, facilitating further chemical transformations.

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Bromoacetyl chloride (BrCH2COCl) — chemical structure, CAS 22118-09-8; Chemistry, fine chemical supplied by Tech Serve Solutions
Acid HalidesBuilding BlocksCarbonyl CompoundsChemical SynthesisOrganic Building Blocks
01 /Applications

Organic Synthesis Intermediate

Bromoacetyl chloride is widely used as an intermediate in the synthesis of more complex organic molecules. Its reactive nature allows for efficient acylation reactions, forming new carbon-carbon or carbon-heteroatom bonds.

Pharmaceutical Research

This compound acts as a key building block in the development of novel pharmaceutical agents. It is instrumental in constructing molecular frameworks found in various drug candidates.

Agrochemical Development

In the agrochemical sector, bromoacetyl chloride finds application in the synthesis of active ingredients for pesticides and herbicides, contributing to crop protection solutions.

02 /Properties
Molecular weight157.39
Linear formulaBrCH2COCl
Assay≥95% (GC)
Boiling point127-128 °C(lit.)
Density1.89 g/mL at 20 °C
Refractive indexn20/D 1.495
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Transport (UN / ADR)UN 3265 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)14-34-37
Safety statements (S)26-36/37/39-45
Supplemental hazardsReacts violently with water.

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
22118-09-8
MDL number
MFCD00000724
Beilstein registry
1209323
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Bromoacetyl chloride used for?

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Bromoacetyl chloride is primarily used as an intermediate and building block in organic synthesis, particularly in the pharmaceutical and agrochemical industries for creating complex molecules.

What are the CAS number and formula for Bromoacetyl chloride?

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The CAS number for Bromoacetyl chloride is 22118-09-8, and its linear formula is BrCH₂COCl.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Bromoacetyl chloride with a minimum purity of 95% as determined by GC. This product is supplied for research and industrial use and is not represented as USP, BP, or EP grade.

How should Bromoacetyl chloride be handled safely?

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Bromoacetyl chloride is a corrosive substance that reacts violently with water and can cause severe skin burns and eye damage. It is also irritating to the respiratory tract. Appropriate personal protective equipment, including face shields, gloves, goggles, and suitable respiratory protection, must be used. Handle only in well-ventilated areas or under a fume hood.

How is Bromoacetyl chloride packed and shipped?

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Bromoacetyl chloride is shipped as a UN 3265, Class 8, Packing Group II hazardous material, suitable for international export.

How can I request a quote or sample?

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To request a quote or sample of Bromoacetyl chloride, please contact our sales team through the website or by phone.

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