Bromobenzene
Bromobenzene (CAS: 108-86-1), with the molecular formula C6H5Br and a molecular weight of 157.01 g/mol, is a clear, colourless to pale yellow liquid. This halogenated aromatic hydrocarbon is a versatile building block in organic synthesis. It is primarily used as an intermediate in the production of pharmaceuticals, agrochemicals, and other complex organic molecules, serving as a key reagent in various chemical transformations.
Organic Synthesis Intermediate
Bromobenzene serves as a crucial intermediate in a wide range of organic syntheses. It is frequently employed in Grignard reactions and Suzuki couplings to introduce the phenyl group into target molecules, facilitating the construction of more complex organic structures.
Polymer Science
In polymer chemistry, bromobenzene has been utilised in the synthesis of specific functional polymers. For instance, it was used in creating a four-armed star chain transfer agent for the preparation of amphiphilic star graft copolymers.
Pharmaceutical and Agrochemical Precursor
This compound acts as a precursor in the multi-step synthesis of various active pharmaceutical ingredients (APIs) and agrochemicals. Its reactivity allows for the controlled introduction of phenyl moieties essential for biological activity.
| Molecular weight | 157.01 |
|---|---|
| Empirical formula | C6H5Br |
| Assay | ≥99.5% (GC) |
| Boiling point | 156 °C(lit.) |
| Density | 1.491 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.559(lit.)n20/D 1.559 |
| Solubility | alcohol: soluble10.4g/100g at 25 °Cdiethyl ether: soluble71.3g/100g at 25 °Cwater: insoluble0.045g/100g at 30 °C (practically)benzene: misciblechloroform: misciblehydrocarbons: miscible (petr.) |
| Melting point | −31 °C(lit.) |
| Vapour pressure | 10 mmHg (40 °C) |
| Vapour density | 5.41 (vs air) |
| Autoignition temp | 1051 °F |
| Application | Bromobenzene was used in the synthesis of four-armed star chain transfer agent required for preparation of amphiphilic star graft copolymers1. |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 51 °C / 123.8 °F |
| Transport (UN / ADR) | UN 2514 3 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi,N |
| Risk statements (R) | 10-38-51/53 |
| Safety statements (S) | 61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Expl Lim | 36.5 % |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bromobenzene used for?
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Bromobenzene is primarily used as an intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and in polymer science applications. It is a key reagent for introducing phenyl groups into molecules via reactions like Grignard and Suzuki couplings.
What is the CAS number and chemical formula for Bromobenzene?
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The CAS number for Bromobenzene is 108-86-1, and its chemical formula is C6H5Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bromobenzene with an assay of ≥99.5% (GC). This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should Bromobenzene be handled safely?
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Bromobenzene is a flammable liquid and vapour (H226) and can cause skin irritation (H315). It is also toxic to aquatic life with long-lasting effects (H411). Handle in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment, including eye protection, gloves, and a suitable respirator. Avoid release to the environment (P273).
Is Bromobenzene a controlled substance?
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The provided data does not indicate that Bromobenzene is a controlled substance. However, users should always comply with local regulations.
How is Bromobenzene typically packed and shipped?
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Bromobenzene is shipped in compliance with international regulations for hazardous materials. Specific packaging details can be provided upon request.
How can I request a quote or sample of Bromobenzene?
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To request a quote or a sample of Bromobenzene, please contact our sales team through our website or by phone. Provide the product name and CAS number (108-86-1) for prompt service.
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