BRL 50481

CAS 433695-36-4C9H12N2O4SBiochemicals & Reagents

BRL 50481 (CAS 433695-36-4) is a chemical compound with the molecular formula C9H12N2O4S and a molecular weight of 244.27 g/mol. It is supplied as a white to off-white solid. This molecule is recognised for its role as a phosphodiesterase 7 inhibitor, positioning it as a valuable tool in biochemical research and drug discovery, particularly within cell signalling and neuroscience research areas. TSS provides this compound for research purposes.

IUPAC: 5-Nitro-2,N,N-trimethylbenzenesulfonamide

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BRL 50481 (C9H12N2O4S) — chemical structure, CAS 433695-36-4; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCell BiologyEnzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymesInhibitorsand SubstratesGlaxoSmithKlineP to Q

01 /Applications

Phosphodiesterase 7 Inhibition

BRL 50481 acts as a selective inhibitor of phosphodiesterase 7 (PDE7) enzymes. This inhibitory action is critical for understanding cellular signalling pathways, particularly in inflammatory and immune responses.

Cellular Signalling Research

As a bioactive small molecule, BRL 50481 is utilized in studies investigating cyclic nucleotide signalling. Its ability to modulate PDE activity makes it useful for dissecting complex intracellular communication networks.

Drug Discovery and Development

This compound is identified as an approved therapeutic/drug candidate. It serves as a valuable reference standard or research tool in the early stages of developing new therapeutic agents targeting PDE7-related conditions.

Biochemical Assays

BRL 50481 is employed in various biochemical assays to validate enzyme activity or screen for compounds that modulate phosphodiesterase function. Its defined inhibitory profile aids in experimental design.

02 /Properties

Molecular weight	244.27
Empirical formula	C9H12N2O4S
Assay	≥98% (HPLC)
Form	solid
Colour	white to off-white
Solubility	DMSO: >10 mg/mLH2O: insoluble
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

433695-36-4

MDL number

MFCD03039912

05 /Additional specifications

Gene Information	human ... PDE7A(5150), PDE7B(27115)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is BRL 50481 used for?

BRL 50481 is used as a research chemical, specifically as a phosphodiesterase 7 inhibitor for studies in cell signalling, neuroscience, and drug discovery.

What are the CAS number and formula for BRL 50481?

The CAS number for BRL 50481 is 433695-36-4, and its molecular formula is C9H12N2O4S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies BRL 50481 with an assay of ≥98% by HPLC. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety and handling considerations for BRL 50481?

Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used when handling BRL 50481. It has a WGK Germany rating of 3.

How is BRL 50481 shipped and exported?

BRL 50481 is typically stored at 2-8°C and shipped according to standard chemical handling protocols. TSS is a global supplier and exporter experienced in international chemical logistics.

How can I request a quote or sample for BRL 50481?

To request a quote or sample for BRL 50481, please contact our sales team through the TSS website or by phone, providing the product name and CAS number.