BQ-788
BQ-788 (CAS: 156161-89-6), a complex organic sodium salt with the formula C34H50N5NaO7, is a potent endothelin receptor antagonist. It presents as a white solid and is primarily utilised in scientific research for its specific biological activity. Its molecular weight is 663.78 g/mol. BQ-788 serves as a valuable tool in cellular signalling studies, particularly those investigating endothelin pathways and their physiological roles.
- IUPAC
- 2,6-Dimethylpiperidinecarbonyl-γ-Methyl-Leu-Nin-(Methoxycarbonyl)-D-Trp-D-Nle,N-[N-[N-[(2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl]-1-(methoxycarbonyl)-D-tryptophyl]-D-norleucine sodium salt
Endothelin Receptor Antagonism
BQ-788 acts as a specific antagonist for endothelin receptors, making it a crucial reagent for studying the biological effects of endothelin in various physiological and pathological processes. Its selectivity aids in dissecting receptor-mediated signalling.
Cellular Signalling Research
This compound is employed in cell biology research to investigate signalling cascades involving endothelin, particularly in cardiovascular and neurological research. It helps researchers understand receptor-ligand interactions and downstream effects.
Pharmacological Tool
As a well-defined bioactive small molecule, BQ-788 is used as a pharmacological tool to modulate endothelin receptor activity in experimental settings. It assists in the validation of targets and the study of potential therapeutic interventions.
| Molecular weight | 663.78 |
|---|---|
| Empirical formula | C34H50N5NaO7 |
| Assay | ≥95% |
| Form | solid |
| Colour | white |
| Solubility | acetonitrile: soluble0.3 mg/mLDMSO: soluble1.2 mg/mLethanol: soluble1.2 mg/mLH2O: slightly soluble |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... EDNRB(1910)mouse ... EDNRB(13618)rat ... EDNRB(50672) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is BQ-788 used for?
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BQ-788 is primarily used as an endothelin receptor antagonist in scientific research, particularly for investigating cellular signalling pathways and as a pharmacological tool in cell biology studies.
What is the CAS number and chemical formula for BQ-788?
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The CAS number for BQ-788 is 156161-89-6, and its chemical formula is C34H50N5NaO7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies BQ-788 with an assay of ≥95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should BQ-788 be handled and stored?
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BQ-788 should be handled using appropriate personal protective equipment, including eyeshields and gloves, and with respiratory protection such as a type N95 (US) or P1 (EN143) filter respirator. It should be stored at -20°C.
Is BQ-788 a controlled substance?
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The provided data does not indicate that BQ-788 is a controlled substance.
How is BQ-788 shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, equipped to handle international shipments of BQ-788.
How can I request a sample or quote for BQ-788?
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Please contact the Tech Serve Solutions sales team to request a sample or a quote for BQ-788. Details for contacting sales can be found on our website.
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