Bongkrekic acid solution
Bongkrekic acid solution (CAS: 11076-19-0, Formula: C28H38O7, MW: 486.60) is a potent inhibitor of the mitochondrial adenine nucleotide translocase (ANT). Derived from the bacterium Pseudomonas cocovenenans, this solution is primarily utilised in biochemical research for studying mitochondrial function, apoptosis, and energy metabolism. Its specific inhibitory action makes it a valuable tool for probing cellular energy pathways and associated disease mechanisms.
Mitochondrial Respiration Studies
Used to investigate the role of adenine nucleotide translocase (ANT) in mitochondrial respiration and ATP production. Bongkrekic acid effectively blocks the exchange of ADP and ATP across the inner mitochondrial membrane, allowing researchers to isolate specific components of the electron transport chain.
Apoptosis Research
Serves as a tool to induce or study the mechanisms of apoptosis, particularly those pathways involving mitochondrial outer membrane permeabilization. By disrupting mitochondrial function, it can trigger programmed cell death, aiding in the understanding of cellular survival and death signaling.
Cellular Energy Metabolism Analysis
Investigates the intricate balance of cellular energy production and consumption. Its inhibitory effect on ANT helps elucidate the dependence of various cellular processes on mitochondrial ATP output.
| Molecular weight | 486.60 |
|---|---|
| Empirical formula | C28H38O7 |
| Assay | ≥95% (HPLC) |
| Concentration | ~1 mg/mL |
| Storage temperature | −20°C |
| Biological source | from Pseudomonas cocovenenans |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | wet ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bongkrekic acid solution used for?
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Bongkrekic acid solution is primarily used in biochemical research to study mitochondrial function, specifically its potent inhibition of the adenine nucleotide translocase (ANT). It is also employed in research concerning apoptosis and cellular energy metabolism.
What is the CAS number and formula for Bongkrekic acid solution?
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The CAS number for Bongkrekic acid solution is 11076-19-0, and its empirical formula is C28H38O7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bongkrekic acid solution with an assay of ≥95% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What safety precautions should be taken when handling Bongkrekic acid solution?
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When handling Bongkrekic acid solution, it is essential to use safety equipment including eyeshields, gloves, and appropriate respiratory protection (half-mask respirator EU/US, or multi-purpose combination respirator cartridge US) due to potential hazards.
How is Bongkrekic acid solution shipped and stored?
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Bongkrekic acid solution is shipped in wet ice and should be stored at −20°C to maintain its stability and efficacy.
How can I request a sample or quote for Bongkrekic acid solution?
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To request a sample or a quote for Bongkrekic acid solution, please contact our sales department via the website or provide your details through the inquiry form.
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