Boc-Val-Pro-Arg-7-amido-4-methylcoumarin hydrochloride
Boc-Val-Pro-Arg-7-amido-4-methylcoumarin hydrochloride (CAS: 70375-24-5) is a fluorogenic peptide substrate with the molecular formula C31H45N7O7 and a molecular weight of 627.73. This compound is primarily utilised as a sensitive assay substrate in biochemical research. It is particularly employed for the detection and quantification of proteolytic enzyme activity, specifically in studies involving thrombin and other serine proteases. Its reliable performance makes it a valuable reagent in cell biology and cell signalling research.
Enzyme Activity Assays
Serves as a fluorogenic substrate for assaying the activity of specific proteases, such as thrombin. The release of the 7-amido-4-methylcoumarin (AMC) fluorophore upon cleavage allows for sensitive detection and quantification of enzyme kinetics.
Biochemical Research
A valuable tool in biochemical and enzymatic studies, enabling researchers to investigate proteinase function and inhibition. It is widely used in the study of coagulation pathways and related biological processes.
Cell Biology Studies
Applied in cell biology to investigate intracellular enzyme activity and signalling pathways. Its use helps elucidate the roles of specific proteases in cellular functions and responses.
Drug Discovery and Development
Can be utilised in screening assays for identifying novel protease inhibitors. Its specificity allows for efficient evaluation of potential therapeutic compounds targeting protease activity.
| Molecular weight | 627.73 |
|---|---|
| Empirical formula | C31H45N7O7 |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Val-Pro-Arg-7-amido-4-methylcoumarin hydrochloride used for?
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This compound is used as a fluorogenic substrate for the detection and quantification of proteolytic enzyme activity, particularly for enzymes like thrombin, in biochemical research, cell biology, and drug discovery.
What are the CAS number and molecular formula?
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The CAS number is 70375-24-5, and the molecular formula is C31H45N7O7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research and laboratory use. The specific grade and purity are detailed in the product specifications. We do not represent this product as USP, BP, EP, or for pharmaceutical, food, or nutraceutical use.
How should Boc-Val-Pro-Arg-7-amido-4-methylcoumarin hydrochloride be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at -20°C to maintain stability.
Is Boc-Val-Pro-Arg-7-amido-4-methylcoumarin hydrochloride a hazardous substance?
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According to GHS information, this compound has a WGK Germany classification of 3, indicating it is hazardous.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Products are packed and shipped according to international regulations for hazardous materials to ensure safe transport worldwide.
How can I request a sample or a quote?
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To request a sample or obtain a quote for Boc-Val-Pro-Arg-7-amido-4-methylcoumarin hydrochloride, please contact our sales department through the website or via direct inquiry, providing your specific requirements.
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