Boc-Phe-OH
N-(tert-Butoxycarbonyl)-L-phenylalanine (Boc-Phe-OH), CAS 13734-34-4, is a protected amino acid derivative with the linear formula CââââÂ16H23NO4 and a molecular weight of 265.30 g/mol. It is widely employed in peptide synthesis as a building block for introducing phenylalanine residues. Its tert-butoxycarbonyl (Boc) protecting group allows for controlled peptide chain elongation, making it a valuable reagent in organic synthesis and biochemical research.
- IUPAC
- N-(tert-Butoxycarbonyl)-L-phenylalanine,Boc-L-phenylalanine
- Synonyms
- N-(tert-Butoxycarbonyl)-L-phenylalanineBoc-L-phenylalanine

Peptide Synthesis
Boc-Phe-OH serves as a crucial protected amino acid in solid-phase and solution-phase peptide synthesis. The Boc group facilitates selective coupling and deprotection strategies, enabling the construction of complex peptide sequences.
Organic Synthesis Reagent
This compound is utilized as a chiral building block in various organic synthesis pathways. Its defined stereochemistry and protected functional groups are advantageous for creating stereospecific target molecules.
Biochemical Research
As a derivative of the essential amino acid phenylalanine, Boc-Phe-OH is employed in studies involving protein structure, enzyme mechanisms, and the development of peptidomimetics.
| Molecular weight | 265.30 |
|---|---|
| Linear formula | C6H5CH2CH(COOH)NHCOOC(CH3)3 |
| Assay | ≥99.0% (T) |
| Optical activity | [α]20/D +25±1°, c = 1% in ethanol |
| Melting point | 85-87 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Phe-OH used for?
+
Boc-Phe-OH is primarily used as a protected amino acid building block in peptide synthesis and as a chiral reagent in organic synthesis and biochemical research.
What is the CAS number and formula for Boc-Phe-OH?
+
The CAS number for Boc-Phe-OH is 13734-34-4, and its linear formula is CââââÂ16H23NO4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Boc-Phe-OH with an assay of â?¥99.0% (T). This is a high-purity grade suitable for research and synthesis. We do not represent this product as USP, BP, or EP grade unless explicitly stated in the specifications.
What are the safety considerations for handling Boc-Phe-OH?
+
Handle Boc-Phe-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the safety data sheet for comprehensive handling information. It is classified with WGK Germany rating 3.
How is Boc-Phe-OH packed and shipped?
+
Tech Serve Solutions expertly packs and ships fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all necessary safety and export regulations.
How can I request a sample or quote for Boc-Phe-OH?
+
To request a sample or a quote for Boc-Phe-OH, please contact our sales team through the website or by calling us directly.
▶ Related products

Benzeneruthenium(II) chloride dimer
Ru2(C6H6)2Cl4
Catalysis & Inorganic
Benzoylferrocene
C17H14FeO
Catalysis & Inorganic
Benzyldiphenylphosphine
C6H5CH2P(C6H5)2
Catalysis & Inorganic
Beryllium
Be
Catalysis & Inorganic
Beryllium oxide
BeO
Catalysis & Inorganic![Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer — chemical structure, CAS 12257-42-0; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F12257-42-0.png&w=3840&q=75)
Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer
Catalysis & Inorganic
![Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo — chemical structure, CAS 1228149-03-8; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1228149-03-8.png&w=3840&q=75)
Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo
1-d:1′
Catalysis & Inorganic![Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride (C16H20ClN3Ni) — chemical structure, CAS 1033772-47-2; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1033772-47-2.png&w=3840&q=75)
Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride
C16H20ClN3Ni
Catalysis & Inorganic▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis