Boc-D-Cha-OH hydrate
Boc-D-Cha-OH hydrate (CAS: 127095-92-5), with the empirical formula C14H25NO4 · xH2O and a molecular weight of 271.35 g/mol (anhydrous basis), is a protected amino acid derivative. This compound serves as a valuable building block in organic synthesis, particularly in the field of peptide chemistry. It is frequently employed in the construction of peptides and peptidomimetics where the D-cyclohexylalanine moiety is incorporated.
- IUPAC
- Boc-3-cyclohexyl-D-alanine hydrate,Boc-hexahydro-D-phenylalanine
- Synonyms
- Boc-3-cyclohexyl-D-alanine hydrate,Boc-hexahydro-D-phenylalanine
Peptide Synthesis
Boc-D-Cha-OH hydrate is a crucial reagent in solid-phase and solution-phase peptide synthesis. It allows for the controlled introduction of the unnatural amino acid D-cyclohexylalanine into peptide chains, enabling the study of structure-activity relationships.
Chemical Biology Research
This compound is utilised in chemical biology for creating modified peptides with altered conformational properties or enhanced stability. Its incorporation can lead to novel biomolecules for probing biological systems.
Organic Synthesis Building Block
Beyond peptides, Boc-D-Cha-OH hydrate acts as a versatile building block in general organic synthesis. It provides a chiral centre and a protected amino acid functionality for constructing complex organic molecules.
Drug Discovery and Development
In the pharmaceutical sector, this derivative is employed in the design and synthesis of peptidomimetics and drug candidates. Its unique structure can confer desirable pharmacological properties.
| Molecular weight | 271.35 (anhydrous basis) |
|---|---|
| Empirical formula | C14H25NO4 · xH2O |
| Optical activity | [α]20/D +15.5±1°, c = 2% in glacial acetic acid |
| Impurities tested | ~1 mol/mol water |
| Melting point | 64-67 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-Cha-OH hydrate used for?
+
Boc-D-Cha-OH hydrate is primarily used as a protected amino acid derivative in peptide synthesis, chemical biology research, general organic synthesis, and drug discovery to introduce the unnatural D-cyclohexylalanine moiety into molecules.
What is the CAS number and formula for Boc-D-Cha-OH hydrate?
+
The CAS number for Boc-D-Cha-OH hydrate is 127095-92-5, and its empirical formula is C14H25NO4 · xH2O.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Boc-D-Cha-OH hydrate with a purity of approximately 95% (anhydrous basis), with impurities of ~1 mol/mol water. This product is intended for research and development purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Boc-D-Cha-OH hydrate be handled safely?
+
When handling Boc-D-Cha-OH hydrate, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. In environments where dust or aerosols may be generated, a type N95 (US) or type P1 (EN143) respirator filter should be used. It is classified with WGK Germany 3, indicating a high hazard to water.
How is Boc-D-Cha-OH hydrate shipped and exported?
+
Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Boc-D-Cha-OH hydrate, adhering to all necessary regulations for international shipping.
How can I request a sample or quote for Boc-D-Cha-OH hydrate?
+
To request a sample or a quote for Boc-D-Cha-OH hydrate, please contact our sales team through the website or by phone, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis