Boc-D-Asp(OBzl)-OH

CAS 51186-58-4C6H5CH2O2CCH2CH[NHCO2C(CH3)3]CO2HChemical Synthesis

Boc-D-Asp(OBzl)-OH (CAS 51186-58-4) is a protected derivative of the amino acid aspartic acid. It features a tert-butyloxycarbonyl (Boc) protecting group on the alpha-amino group and a benzyl ester protecting group on the beta-carboxyl group. This structure makes it a valuable building block in solid-phase peptide synthesis and for the construction of complex organic molecules. Its defined stereochemistry (D-configuration) is crucial for specific peptide sequences.

IUPAC: Boc-D-aspartic acid 4-benzyl ester

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Boc-D-Asp(OBzl)-OH (C6H5CH2O2CCH2CH[NHCO2C(CH3)3]CO2H) — chemical structure, CAS 51186-58-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesAspartic AcidChemical BiologyChemical SynthesisPeptide Chemistry

01 /Applications

Peptide Synthesis

Boc-D-Asp(OBzl)-OH serves as a key protected amino acid in solid-phase and solution-phase peptide synthesis. The Boc and benzyl ester groups allow for selective deprotection and coupling reactions during the assembly of peptide chains, particularly when incorporating D-aspartic acid residues.

Organic Synthesis

This compound is utilised as a chiral building block in the synthesis of complex organic molecules. Its protected functional groups enable precise chemical modifications and the creation of stereochemically defined intermediates for pharmaceutical and chemical research.

Chemical Biology

In chemical biology, Boc-D-Asp(OBzl)-OH can be incorporated into peptides or peptidomimetics to study biological processes or to develop novel therapeutic agents. The D-amino acid configuration offers resistance to enzymatic degradation compared to L-amino acids.

02 /Properties

Molecular weight	323.34
Linear formula	C6H5CH2O2CCH2CH[NHCO2C(CH3)3]CO2H
Assay	≥98.0% (HPLC)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

51186-58-4

MDL number

MFCD00038255

Beilstein registry

2305471

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-D-Asp(OBzl)-OH used for?

Boc-D-Asp(OBzl)-OH is primarily used as a protected building block in peptide synthesis and for the construction of complex organic molecules in chemical and pharmaceutical research.

What is the CAS number and formula for Boc-D-Asp(OBzl)-OH?

The CAS number is 51186-58-4. The linear formula is C6H5CH2O2CCH2CH[NHCO2C(CH3)3]CO2H.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Boc-D-Asp(OBzl)-OH with a purity of ≥98.0% (HPLC). TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade.

What are the safety and handling precautions for Boc-D-Asp(OBzl)-OH?

Handling this compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It carries a WGK 3 (Germany) hazard classification, indicating a high degree of hazard to water.

How is Boc-D-Asp(OBzl)-OH packed, shipped, and exported?

Tech Serve Solutions carefully packs and ships chemicals globally, adhering to all relevant international regulations for hazardous materials. We are experienced exporters of fine chemicals.

How can I request a sample or quote for Boc-D-Asp(OBzl)-OH?

To request a sample or a quote, please visit the 'Contact Us' section of the Tech Serve Solutions website or email our sales department directly with your inquiry.